Date published: 2025-9-6

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TRPC3 抗体 (C-5): sc-514670

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说明书
  • TRPC3 抗体 C-5 是小鼠单克隆 IgG2a κ,TRPC3抗体, 在10篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列1-100位于human物种的TRPC3的N-terminus
  • TRPC3 抗体 (C-5) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 TRPC3
  • 抗TRPC3抗体(C-5)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取TRPC3 (C-5): sc-514670免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是TRPC3 Antibody (C-5) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与TRPC3 Antibody (C-5) 打包提供(请参阅下面的订购信息)。

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関連項目

TRPC3抗体(C-5)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的TRPC3蛋白。TRPC3 (C-5) 抗体有非结合型和多种结合型可供选择,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物。瞬时受体电位阳离子(TRPC)通道是细胞内钙稳态调节不可或缺的一部分,在储存操作钙进入中起着至关重要的作用。这一过程对于许多细胞功能至关重要,包括肌肉收缩、神经递质释放和基因表达。TRPC3主要在大脑中表达,在大脑中,TRPC3有助于神经信号传导和可塑性。TRPC3的激活与肌醇1,4,5-三磷酸受体和通道本身的相互作用密切相关,可促进钙离子在各种刺激下的涌入。此外,TRPC3还可以通过二酰基甘油激活,而与蛋白激酶C无关,这凸显了TRPC3在各种信号通路中的重要性。了解TRPC3的功能和调节对于阐明TRPC3在生理过程中的作用以及在病理条件下的潜在影响至关重要。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TRPC3 抗体 (C-5) 参考文献:

  1. 从蠕虫到人类:TRP 通道的三个亚家族。  |  Harteneck, C., et al. 2000. Trends Neurosci. 23: 159-66. PMID: 10717675
  2. 瞬时受体电位通道是受体介导的阳离子进入的分子底物。  |  Hofmann, T., et al. 2000. J Mol Med (Berl). 78: 14-25. PMID: 10759026
  3. 瞬时受体电位蛋白同源物TRP6是血管α(1)肾上腺素受体激活的Ca(2+)渗透阳离子通道的重要组成部分。  |  Inoue, R., et al. 2001. Circ Res. 88: 325-32. PMID: 11179201
  4. 人体血小板中 1,4,5-三磷酸肌醇受体 II 型与人类瞬时受体电位(hTrp1)通道之间的分泌耦合激活了贮存介导的钙离子进入。  |  Rosado, JA. and Sage, SO. 2001. Biochem J. 356: 191-8. PMID: 11336651
  5. TRPC3通道是脑源性神经营养因子激活非选择性阳离子电流并诱导树突棘形成的必要条件。  |  Amaral, MD. and Pozzo-Miller, L. 2007. J Neurosci. 27: 5179-89. PMID: 17494704
  6. 自发性高血压大鼠的单核细胞显示出由瞬时受体电位典型 3 型通道介导的贮存作用和第二信使作用钙离子流入增加。  |  Liu, DY., et al. 2007. Am J Hypertens. 20: 1111-8. PMID: 17903696
  7. TRPC1,果蝇存储操作通道的人类同源物。  |  Wes, PD., et al. 1995. Proc Natl Acad Sci U S A. 92: 9652-6. PMID: 7568191
  8. 由钙储存耗竭激活的人类 Ca2+ 渗透性阳离子通道的克隆和功能表达。  |  Zitt, C., et al. 1996. Neuron. 16: 1189-96. PMID: 8663995
  9. 一种在可兴奋细胞中表达的新型容性钙离子通道。  |  Philipp, S., et al. 1998. EMBO J. 17: 4274-82. PMID: 9687496
  10. 二酰甘油对人类 TRPC6 和 TRPC3 通道的直接激活。  |  Hofmann, T., et al. 1999. Nature. 397: 259-63. PMID: 9930701
  11. 二酰甘油和磷脂酰肌醇-4,5-二磷酸对 TRPC3, 6 和 7 通道亚家族的复杂调控。  |  Lemonnier, L., et al. 2008. Cell Calcium. 43: 506-14. PMID: 17942152

订购信息

产品名称产品编号规格价格数量收藏夹

TRPC3 抗体 (C-5)

sc-514670
200 µg/ml
$316.00

TRPC3 (C-5): m-IgG Fc BP-HRP 套装

sc-531188
200 µg Ab; 10 µg BP
$354.00

TRPC3 (C-5): m-IgGκ BP-HRP 套装

sc-524807
200 µg Ab, 40 µg BP
$354.00

TRPC3 (C-5): m-IgG2a BP-HRP 套装

sc-547719
200 µg Ab; 10 µg BP
$354.00

TRPC3 抗体 (C-5) AC

sc-514670 AC
500 µg/ml, 25% agarose
$416.00

TRPC3 抗体 (C-5) HRP

sc-514670 HRP
200 µg/ml
$316.00

TRPC3 抗体 (C-5) FITC

sc-514670 FITC
200 µg/ml
$330.00

TRPC3 抗体 (C-5) PE

sc-514670 PE
200 µg/ml
$343.00

TRPC3 抗体 (C-5) Alexa Fluor® 488

sc-514670 AF488
200 µg/ml
$357.00

TRPC3 抗体 (C-5) Alexa Fluor® 546

sc-514670 AF546
200 µg/ml
$357.00

TRPC3 抗体 (C-5) Alexa Fluor® 594

sc-514670 AF594
200 µg/ml
$357.00

TRPC3 抗体 (C-5) Alexa Fluor® 647

sc-514670 AF647
200 µg/ml
$357.00

TRPC3 抗体 (C-5) Alexa Fluor® 680

sc-514670 AF680
200 µg/ml
$357.00

TRPC3 抗体 (C-5) Alexa Fluor® 790

sc-514670 AF790
200 µg/ml
$357.00

I need to use an antibody to detect the protein in samples of bovine origin. Do you know if sc-514670: TRPC3 (C-5) mouse monoclonal antibody will work?

Asked by: Randy McDonald
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
  • y_2025, m_8, d_27, h_5CST
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Rated 5 out of 5 by from Good antibody1:200 diluted for wb of rat protein,the band is quite strong
Date published: 2020-02-02
Rated 5 out of 5 by from 抗体不错此抗体效价还是不错的,而且没有其他杂带,在100kDa处目的条带清晰,而且可以放四度保存,存取方便,总体而言,还是一款不错的抗体。
Date published: 2018-02-07
Rated 5 out of 5 by from Excellent antibody!TRPC-3 (C5) is an excellent antibody for immunoblotting. The antibody gave two bands in HEK293 and one band in HepG2 cells, equivalent to 95-100kDa which is perfect. The additional band in human HEK293 cells (see the attached blot) may be due to post-transnational modification, depending on the type of modification it may give additional mass to the protein. The HepG2 cell line derived from a human hepatocarcinoma. Excellent antibody, highly recommended.
Date published: 2017-11-14
Rated 5 out of 5 by from Clean bandVery happy result that the TRPC3 antibody shows good quality for western blot with HepG2 cells,Clean band around 100kda.
Date published: 2017-09-02
Rated 3 out of 5 by from 效价较低这个试用装是一年前到货的,WB只压出过一次条带,可能是条带比较大,所以需要的蛋白量也大,自认效价一般。
Date published: 2017-08-17
Rated 5 out of 5 by from Mice are very satisfiedPowerful antibodies and sensitive cell in mice experiment,. It is strongly recommended
Date published: 2017-02-09
Rated 5 out of 5 by from The antibody cell experiment mice,Excellent antibodies of mice and sensitive cell experiments, powerful band at the bank. It is highly recommended.
Date published: 2017-02-03
Rated 4 out of 5 by from TRPC3 Antibodythe antibody works perfect for Western blot rat cell samples
Date published: 2016-12-28
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TRPC3 抗体 (C-5) is rated 4.6 out of 5 by 8.
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