TGase2 Antibody (G-8): sc-48370
- TGase2 Antibody (G-8) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 451-687 of TGase2 of human origin
- recommended for detection of TGase2 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TGase2 Antibody (G-8) for WB applications. These reagents are now offered in bundles with TGase2 Antibody (G-8) (see ordering information below).
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TGase2 Antibody (G-8) is a mouse monoclonal IgG2b antibody that detects human tissue transglutaminase (TGase2) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TGase2 is an endothelial cell-specific protein consisting of 687 amino acids, playing a crucial role in various biological processes, including cell adhesion, migration, and apoptosis. TGase2 function is particularly important in wound healing and tissue repair, as TGase2 facilitates the cross-linking of proteins, thereby stabilizing the extracellular matrix and promoting cellular interactions. TGase2 is involved in the regulation of apoptosis, which is vital for maintaining tissue homeostasis and preventing tumorigenesis. TGase2′s ability to form isopeptide bonds through transglutaminase activity underscores TGase2′s significance in cellular signaling and structural integrity. TGase2 Antibody (G-8) enables researchers to effectively study the expression and functional dynamics of TGase2 in various physiological and pathological contexts.
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TGase2 Antibody (G-8) References:
- Transglutaminase 2 in inflammation. | Kim, SY. 2006. Front Biosci. 11: 3026-35. PMID: 16720373
- Transglutaminase 2 and neuroinflammation. | Ientile, R., et al. 2015. Amino Acids. 47: 19-26. PMID: 25398223
- Transglutaminase 2 and Transglutaminase 2 Autoantibodies in Celiac Disease: a Review. | Rauhavirta, T., et al. 2019. Clin Rev Allergy Immunol. 57: 23-38. PMID: 27263022
- Inhibition or ablation of transglutaminase 2 impairs astrocyte migration. | Monteagudo, A., et al. 2017. Biochem Biophys Res Commun. 482: 942-947. PMID: 27899316
- Recent Progress in the Development of Transglutaminase 2 (TGase2) Inhibitors. | Song, M., et al. 2017. J Med Chem. 60: 554-567. PMID: 28122456
- Transglutaminase 2, a double face enzyme. | Beninati, S., et al. 2017. Amino Acids. 49: 415-423. PMID: 28204961
- Transglutaminase in neurological disease. | Hoffner, G. and Djian, P. 2017. Oncotarget. 8: 55772-55773. PMID: 28915550
- Spotlight on the Transglutaminase 2-Heparan Sulfate Interaction. | Furini, G. and Verderio, EAM. 2019. Med Sci (Basel). 7: PMID: 30621228
- Transglutaminase-Mediated Conjugations. | Anami, Y. and Tsuchikama, K. 2020. Methods Mol Biol. 2078: 71-82. PMID: 31643050
- The Role of Transglutaminase 2 in Cancer: An Update. | Zaltron, E., et al. 2024. Int J Mol Sci. 25: PMID: 38474044
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TGase2 Antibody (G-8) | sc-48370 | 200 µg/ml | $316.00 | |||
TGase2 Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-536818 | 200 µg Ab; 10 µg BP | $354.00 | |||
TGase2 Antibody (G-8): m-IgGκ BP-HRP Bundle | sc-533984 | 200 µg Ab; 40 µg BP | $354.00 | |||
TGase2 Antibody (G-8): m-IgG2b BP-HRP Bundle | sc-549831 | 200 µg Ab; 10 µg BP | $354.00 |