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TACC3 Antibody (E-4) is a mouse monoclonal IgG2b antibody that detects TACC3 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TACC3, a member of the transforming acidic coiled-coil (TACC) protein family, plays a crucial role in cell division and genomic stability maintenance, making TACC3 essential for proper cellular function and development. TACC3 is primarily located in the cytoplasm and interacts with microtubules, which are vital for mitotic spindle formation during cell division. Proper TACC3 localization ensures accurate chromosome segregation into daughter cells, preventing aneuploidy, a condition often associated with cancer. TACC3 has been implicated in various signaling pathways that regulate cell growth and differentiation, further underscoring TACC3′s significance in tumorigenesis. Through interactions with other cell cycle proteins, TACC3 serves as a potential biomarker for cancer progression and a target for therapeutic intervention.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TACC3 Antibody (E-4) | sc-376900 | 200 µg/ml | $322.00 | |||
TACC3 Antibody (E-4): m-IgGκ BP-HRP Bundle | sc-535524 | 200 µg Ab; 40 µg BP | $361.00 | |||
TACC3 Antibody (E-4): m-IgG2b BP-HRP Bundle | sc-549443 | 200 µg Ab; 10 µg BP | $361.00 | |||
TACC3 (E-4) Neutralizing Peptide | sc-376900 P | 100 µg/0.5 ml | $69.00 |