TACC3 Inhibitors
TACC3 inhibitors belong to a specific chemical class of compounds that have been studied and designed to selectively target and inhibit the activity of TACC3, which stands for Transforming Acidic Coiled-Coil Containing Protein 3. TACC3 is a protein that plays a role in cell division and spindle assembly during mitosis, contributing to the proper segregation of chromosomes.
Inhibition of TACC3 aims to disrupt its function in the regulation of microtubule dynamics and mitotic spindle formation, potentially affecting cell division processes. The chemical structures of TACC3 inhibitors can vary, including synthetic small-molecule compounds and natural products that specifically interact with TACC3 and interfere with its activity or interaction with other proteins involved in spindle assembly. Researchers have explored various strategies to target TACC3 and attenuate its effects on mitosis, a crucial process for proper cell division and genomic stability. The study of TACC3 inhibitors provides valuable insights into the complex regulatory mechanisms governing mitotic processes and cellular proliferation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Taxol investigated for its inhibitory effects on TACC3, particularly its role in stabilizing microtubules during mitosis. | ||||||
Siomycin A | 12656-09-6 | sc-202339 sc-202339-CW sc-202339A sc-202339B | 500 µg 500 µg 2.5 mg 25 mg | $450.00 $500.00 $1350.00 $10404.00 | 4 | |
Siomycin A is a cyclic depsipeptide that has been explored for its potential to inhibit TACC3 and its interaction with the mitotic kinase Aurora A. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
This is a synthetic compound that has been studied for its inhibitory effects on Aurora A kinase, which is associated with TACC3 in mitotic spindle regulation. | ||||||