SPATA20 Antibody (H-10): sc-515190
- SPATA20 Antibody (H-10) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 225-357 mapping within an internal region of SPATA20 of human origin
- recommended for detection of SPATA20 of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SPATA20 Antibody (H-10) for WB applications. These reagents are now offered in bundles with SPATA20 Antibody (H-10) (see ordering information below).
SPATA20 Antibody (H-10) is a mouse monoclonal IgG1 antibody that detects SPATA20 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SPATA20, also known as SP411 or Tisp78, is a 786 amino acid protein that plays a crucial role in fertility regulation, particularly during spermatogenesis. SPATA20 is expressed in the testis in an age-dependent manner and is localized to round and elongated spermatids, highlighting SPATA20′s importance in male reproductive health. The presence of a conserved thioredoxin-like domain near the N-terminus suggests SPATA20 may be involved in redox regulation, which is vital for maintaining cellular homeostasis and protecting cells from oxidative stress. Additionally, SPATA20 exists as four isoforms due to alternative splicing, which may contribute to functional diversity in different cellular contexts. Encoded by a gene located on human chromosome 17, which harbors significant tumor suppressor genes like p53 and BRCA1, SPATA20′s role in fertility may also intersect with broader implications in cancer biology, as disruptions in these pathways can lead to malignancies. Anti-SPATA20 antibody (H-10) serves as an essential tool for researchers investigating the intricate mechanisms of spermatogenesis and potential links to fertility and cancer.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SPATA20 Antibody (H-10) | sc-515190 | 200 µg/ml | $316.00 | |||
SPATA20 Antibody (H-10): m-IgG Fc BP-HRP Bundle | sc-538757 | 200 µg Ab; 10 µg BP | $354.00 | |||
SPATA20 Antibody (H-10): m-IgGκ BP-HRP Bundle | sc-536425 | 200 µg Ab; 40 µg BP | $354.00 | |||
SPATA20 Antibody (H-10): m-IgG1 BP-HRP Bundle | sc-545868 | 200 µg Ab; 20 µg BP | $354.00 |