Smad4 Antibody (SMD46): sc-56775
- Smad4 Antibody (SMD46) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against recombinant Smad4 of human origin
- recommended for detection of Smad4 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See Smad4 (B-8): sc-7966 for Smad4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Smad4 Antibody (SMD46) for WB and IHC(P) applications. These reagents are now offered in bundles with Smad4 Antibody (SMD46) (see ordering information below).
Smad4 Antibody (SMD46) is a mouse monoclonal IgG1 antibody that detects Smad4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Smad4, also known as DPC4, plays a crucial role as a central mediator in the transforming growth factor-beta (TGF-β) and bone morphogenetic protein (BMP) signaling pathways, which are essential for regulating cellular processes such as proliferation, differentiation, and apoptosis. Anti-Smad4 antibody (SMD46) enables detection of protein interactions with various Smad family members, facilitating the transcriptional regulation of target genes in response to TGF-β and BMP signals. These interactions are vital for maintaining normal cellular functions and tissue homeostasis, and dysregulation of Smad4 has been implicated in various diseases, including cancer. Smad4 monoclonal antibody (SMD46) helps researchers effectively study the dynamics of TGF-β/BMP signaling and its implications in health and disease, providing insights that could lead to novel therapeutic strategies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Smad4 Antibody (SMD46) | sc-56775 | 200 µg/ml | $316.00 | |||
Smad4 Antibody (SMD46): m-IgG Fc BP-HRP Bundle | sc-537118 | 200 µg Ab; 10 µg BP | $354.00 | |||
Smad4 Antibody (SMD46): m-IgGκ BP-HRP Bundle | sc-534310 | 200 µg Ab; 40 µg BP | $354.00 | |||
Smad4 Antibody (SMD46): m-IgG1 BP-HRP Bundle | sc-545014 | 200 µg Ab; 20 µg BP | $354.00 |