SERCA2 Antibody (4i351): sc-73022
- SERCA2 Antibody (4i351) is a mouse monoclonal IgG1 κ, cited in 9 publications, provided at 200 µg/ml
- raised against purified canine cardiac sarcoplasmic reticulum
- recommended for detection of SERCA2 of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including and canine, bovine and porcine
- See SERCA2 (F-1): sc-376235 for SERCA2 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SERCA2 Antibody (4i351) for WB applications. These reagents are now offered in bundles with SERCA2 Antibody (4i351) (see ordering information below).
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SERCA2 Antibody (4i351) is a mouse monoclonal IgG1 antibody that detects SERCA2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). SERCA2, a member of the sarcoplasmic or endoplasmic reticulum calcium ATPase (SERCA) family, plays a pivotal role in calcium homeostasis by mediating Ca2+ uptake into the sarcoplasmic reticulum, which is essential for muscle contraction and relaxation. SERCA2 maintains cardiac contractile function by regulating intracellular calcium levels, influencing heartbeat strength and rhythm. SERCA2 exists in two main isoforms: SERCA2a, predominantly expressed in type I (slow) skeletal muscle, cardiac muscle, and smooth muscle, and SERCA2b, found in all cell types. Expression of SERCA2 remains tightly regulated and responds to various physiological conditions, making SERCA2 a key player in muscle physiology and a potential target for therapeutic interventions in cardiac diseases. Anti-SERCA2 antibody (4i351) serves as an invaluable tool for researchers studying calcium signaling pathways and muscle function, providing reliable detection and characterization in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SERCA2 Antibody (4i351) | sc-73022 | 200 µg/ml | $322.00 | |||
SERCA2 Antibody (4i351): m-IgG Fc BP-HRP Bundle | sc-537213 | 200 µg Ab; 10 µg BP | $361.00 | |||
SERCA2 Antibody (4i351): m-IgGκ BP-HRP Bundle | sc-534423 | 200 µg Ab; 40 µg BP | $361.00 | |||
SERCA2 Antibody (4i351): m-IgG1 BP-HRP Bundle | sc-545083 | 200 µg Ab; 20 µg BP | $361.00 |