PSMD12 Antibody (H-8): sc-393401
- PSMD12 Antibody (H-8) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 3-14 at the N-terminus of PSMD12 of human origin
- recommended for detection of PSMD12 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PSMD12 Antibody (H-8) for WB applications. These reagents are now offered in bundles with PSMD12 Antibody (H-8) (see ordering information below).
PSMD12 Antibody (H-8) is a mouse monoclonal IgG2a antibody that detects PSMD12 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PSMD12, also known as p55 or Rpn5, is a crucial regulatory subunit of the 26S proteasome, a complex responsible for the selective degradation of ubiquitinated proteins, which is vital for maintaining cellular homeostasis and regulating various cellular processes, including the cell cycle and apoptosis. PSMD12 consists of 456 amino acids and features a PCI domain, which is essential for its role in the assembly and function of the proteasome. Through interactions with other subunits of the 26S proteasome, PSMD12 facilitates the recognition and unfolding of ubiquitinated substrates, ensuring efficient degradation. This process is critical for removing damaged or misfolded proteins, thereby preventing accumulation of potentially toxic proteins within cells. Anti-PSMD12 antibody (H-8) provides a reliable tool for researchers studying proteasome function and its implications in various diseases, including cancer and neurodegenerative disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PSMD12 Antibody (H-8) | sc-393401 | 200 µg/ml | $322.00 | |||
PSMD12 Antibody (H-8): m-IgG Fc BP-HRP Bundle | sc-538207 | 200 µg Ab; 10 µg BP | $361.00 | |||
PSMD12 Antibody (H-8): m-IgGκ BP-HRP Bundle | sc-535775 | 200 µg Ab; 40 µg BP | $361.00 | |||
PSMD12 Antibody (H-8): m-IgG2a BP-HRP Bundle | sc-548233 | 200 µg Ab; 10 µg BP | $361.00 | |||
PSMD12 (H-8) Neutralizing Peptide | sc-393401 P | 100 µg/0.5 ml | $69.00 |