Progesterone Receptor Antibody (B-30): sc-811
- Progesterone Receptor Antibody (B-30) is a mouse monoclonal IgG1 κ, cited in 28 publications, provided at 200 µg/ml
- recommended for detection of PR-B of human origin by WB, IP and IF
- TransCruz reagent for Gel Supershift and ChIP applications (sc-811 X, 200 µg/0.1 ml)
- See Progesterone Receptor (F-4): sc-166169 for Progesterone Receptor antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Progesterone Receptor Antibody (B-30) for WB applications. These reagents are now offered in bundles with Progesterone Receptor Antibody (B-30) (see ordering information below).
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SEE ALSO...
PR Antibody (B-30) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect the PR-B isoform of the human progesterone receptor, also known as NR3C3, in applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). The progesterone receptor is a pivotal nuclear hormone receptor that binds the steroid hormone progesterone, playing a crucial role in regulating the menstrual cycle, maintaining pregnancy, and supporting embryonic development. Located within the cell nucleus, progesterone receptor functions as a transcription factor, modulating the expression of genes involved in cell growth, differentiation, and apoptosis. Structurally, progesterone receptor comprises distinct domains, including a DNA-binding domain and a ligand-binding domain, which are essential for interaction with specific DNA sequences and responsiveness to hormonal signals. PR-B monoclonal antibody (B-30) targets the PR-B isoform, which acts as a powerful transcriptional activator, influencing pathways critical for reproductive system development and the progression of hormone-responsive cancers such as breast cancer. The PR-A isoform functions as a transcriptional repressor, underscoring the unique and complementary roles of these isoforms in cellular signaling and gene regulation. Understanding the differential functions of PR-B and PR-A is vital for elucidating the complex mechanisms underlying hormone-mediated physiological and pathological processes. PR monoclonal antibody (B-30) enables detailed studies of progesterone-mediated signaling pathways and their implications in various human diseases, making PR (B-30) antibody an essential tool for researchers in the field of endocrinology and oncology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Progesterone Receptor Antibody (B-30) | sc-811 | 200 µg/ml | $316.00 | |||
Progesterone Receptor Antibody (B-30): m-IgG Fc BP-HRP Bundle | sc-536544 | 200 µg Ab; 10 µg BP | $354.00 | |||
Progesterone Receptor Antibody (B-30): m-IgGκ BP-HRP Bundle | sc-533695 | 200 µg Ab; 40 µg BP | $354.00 | |||
Progesterone Receptor Antibody (B-30): m-IgG1 BP-HRP Bundle | sc-544666 | 200 µg Ab; 20 µg BP | $354.00 | |||
Progesterone Receptor Antibody (B-30) X | sc-811 X | 200 µg/0.1 ml | $316.00 |