p-HSP 27 Antibody (D-3): sc-166694
- p-HSP 27 Antibody (D-3) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- recommended for detection of Ser 82 phosphorylated HSP 27 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p-HSP 27 Antibody (D-3) for WB and IHC(P) applications. These reagents are now offered in bundles with p-HSP 27 Antibody (D-3) (see ordering information below).
p-HSP 27 Antibody (D-3) is a mouse monoclonal IgG2b antibody that detects HSP 27 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). anti-HSP 27 antibody (D-3) specifically recognizes the phosphorylated form of HSP 27, a critical heat shock protein that plays a vital role in cellular stress responses. HSP 27 is primarily located in the cytoplasm but translocates to the nucleus under stress conditions, which is essential for its function in protecting cells from apoptosis and promoting cell survival during metabolic stress. HSP 27′s ability to relocate to the nucleus highlights its importance in regulating cellular responses to stress, as HSP 27 can influence gene expression and cellular repair mechanisms. Additionally, HSP 27 undergoes post-translational modifications, including phosphorylation at specific serine residues, which are crucial for activity and interaction with other proteins. For instance, phosphorylation at Serine 15, Serine 78, and Serine 82 enhances chaperone activity and promotes the formation of protein complexes that are vital for cellular protection. HSP 27 monoclonal antibody (D-3) is an invaluable tool for researchers studying the role of HSP 27 in stress response pathways and its implications in various diseases, including cancer and neurodegenerative disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-HSP 27 Antibody (D-3) | sc-166694 | 200 µg/ml | $322.00 | |||
p-HSP 27 Antibody (D-3): m-IgG Fc BP-HRP Bundle | sc-537522 | 200 µg Ab; 10 µg BP | $361.00 | |||
p-HSP 27 Antibody (D-3): m-IgGκ BP-HRP Bundle | sc-534813 | 200 µg Ab; 40 µg BP | $361.00 | |||
p-HSP 27 Antibody (D-3): m-IgG2b BP-HRP Bundle | sc-549884 | 200 µg Ab; 10 µg BP | $361.00 | |||
p-HSP 27 (D-3) Neutralizing Peptide | sc-166694 P | 100 µg/0.5 ml | $69.00 |