p-ARK-2 Antibody (66.Thr 232): sc-293127
- p-ARK-2 Antibody (66.Thr 232) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- raised against a short amino acid sequence containing phosphorylated Thr 232 of ARK-2 of human origin
- recommended for detection of Thr 232 phosphorylated ARK-2 of human origin, and correspondingly phosphorylated Thr 237 ARK-2 of mouse origin, and correspondingly phosphorylated Thr 235 ARK-2 of rat origin by WB, IP and ELISA
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for p-ARK-2 Antibody (66.Thr 232) for WB applications. These reagents are now offered in bundles with p-ARK-2 Antibody (66.Thr 232) (see ordering information below).
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p-ARK-2 Antibody (66.Thr 232) is a mouse monoclonal IgG2b antibody that detects ARK-2 in mouse, rat, and human samples through applications such as western blotting (WB) and enzyme-linked immunosorbent assay (ELISA). anti-ARK-2 antibody (66.Thr 232) specifically recognizes the phosphorylated form of ARK-2 at Threonine 232, a critical post-translational modification that plays a significant role in regulating kinase activity and function during the cell cycle. ARK-2 (66.Thr 232) monoclonal antibody enables detection of phosphorylation at this site, which is essential for autocatalytic activation, influencing centrosome dynamics and spindle assembly during mitosis. This modification ensures proper chromosome segregation, maintaining genomic stability and preventing aneuploidy, a condition often associated with cancer. ARK-2 shows unique expression patterns with maximal protein levels during S and G2/M phases, highlighting a pivotal role in cell cycle progression, while degradation post-mitosis via the ubiquitin-proteasome pathway underscores tightly regulated activity. ARK-2 (66.Thr 232) antibody provides valuable insights into ARK-2′s functional state, making this reagent invaluable for researchers studying cell division and cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-ARK-2 Antibody (66.Thr 232) | sc-293127 | 200 µg/ml | $322.00 | |||
p-ARK-2 Antibody (66.Thr 232): m-IgGκ BP-HRP Bundle | sc-535083 | 200 µg Ab; 40 µg BP | $361.00 | |||
p-ARK-2 Antibody (66.Thr 232): m-IgG2b BP-HRP Bundle | sc-549341 | 200 µg Ab; 10 µg BP | $361.00 |