LKB1 Antibody (E-9): sc-374334
- LKB1 Antibody (E-9) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
- raised against amino acids 1-75 mapping at the N-terminus of LKB1 of human origin
- LKB1 Antibody (E-9) is recommended for detection of LKB1 of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-LKB1 Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for LKB1 Antibody (E-9) for WB and IHC(P) applications. These reagents are now offered in bundles with LKB1 Antibody (E-9) (see ordering information below).
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SEE ALSO...
LKB1 Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody engineered to detect LKB1, also known as STK11 or serine/threonine kinase 11, in human samples using western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-LKB1 antibody (E-9) recognizes an epitope within the first 75 amino acids at the N-terminus of human LKB1, ensuring effective detection across various experimental platforms. LKB1 is a 433 amino acid serine/threonine kinase that plays a crucial role in regulating cellular energy homeostasis, cell polarity, and metabolism by activating AMP-activated protein kinase (AMPK) and other related kinases. Structurally, LKB1 contains a conserved kinase domain essential for enzymatic activity, as well as regulatory regions that facilitate interactions with several key proteins, including STRAD, MO25, and the MARK family kinases. These interactions are vital for proper localization and activation of LKB1, thereby influencing numerous cellular processes such as growth, differentiation, and apoptosis. Mutations in LKB1 are strongly associated with Peutz-Jeghers Syndrome (PJS), a hereditary disorder characterized by benign polyps in the gastrointestinal tract, pigmented spots on the lips, and an increased risk of various cancers. By elucidating the interactions between LKB1 and binding partners, researchers can better understand the molecular mechanisms underlying tumor suppression and metabolic regulation. LKB1 (E-9) antibody is available in both non-conjugated and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, providing versatility for diverse research applications. Anti-LKB1 antibody (E-9) is an essential tool for scientists investigating the intricate network of protein interactions involving LKB1, facilitating advancements in cancer biology, metabolic disease research, and cellular signaling pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
LKB1 Antibody (E-9) | sc-374334 | 200 µg/ml | $316.00 | |||
LKB1 Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-529722 | 200 µg Ab; 10 µg BP | $354.00 | |||
LKB1 Antibody (E-9): m-IgGκ BP-HRP Bundle | sc-522703 | 200 µg Ab, 40 µg BP | $354.00 | |||
LKB1 Antibody (E-9): m-IgG1 BP-HRP Bundle | sc-543652 | 200 µg Ab; 20 µg BP | $354.00 | |||
LKB1 Antibody (E-9) AC | sc-374334 AC | 500 µg/ml, 25% agarose | $416.00 | |||
LKB1 Antibody (E-9) HRP | sc-374334 HRP | 200 µg/ml | $316.00 | |||
LKB1 Antibody (E-9) FITC | sc-374334 FITC | 200 µg/ml | $330.00 | |||
LKB1 Antibody (E-9) PE | sc-374334 PE | 200 µg/ml | $343.00 | |||
LKB1 Antibody (E-9) Alexa Fluor® 488 | sc-374334 AF488 | 200 µg/ml | $357.00 | |||
LKB1 Antibody (E-9) Alexa Fluor® 546 | sc-374334 AF546 | 200 µg/ml | $357.00 | |||
LKB1 Antibody (E-9) Alexa Fluor® 594 | sc-374334 AF594 | 200 µg/ml | $357.00 | |||
LKB1 Antibody (E-9) Alexa Fluor® 647 | sc-374334 AF647 | 200 µg/ml | $357.00 | |||
LKB1 Antibody (E-9) Alexa Fluor® 680 | sc-374334 AF680 | 200 µg/ml | $357.00 | |||
LKB1 Antibody (E-9) Alexa Fluor® 790 | sc-374334 AF790 | 200 µg/ml | $357.00 |