KCTD14 Antibody (A-6): sc-393876
- KCTD14 Antibody (A-6) is a mouse monoclonal IgG2b κ KCTD14 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 132-157 within an internal region of KCTD14 of human origin
- KCTD14 Antibody (A-6) is recommended for detection of KCTD14 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-KCTD14 Antibody (A-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for KCTD14 Antibody (A-6) for WB applications. These reagents are now offered in bundles with KCTD14 Antibody (A-6) (see ordering information below).
KCTD14 Antibody (A-6) is a mouse monoclonal IgG2b kappa light chain antibody that detects KCTD14 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). KCTD14 (A-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. KCTD14 protein consists of 255 amino acids and features a BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as POZ (Poxvirus and Zinc finger) domain, that plays a crucial role in homodimerization and is characterized by multiple kelch repeats and C2H2-type zinc fingers. This structural feature suggests KCTD14 involvement in transcription regulation through chromatin structure and function modulation, influencing gene expression. KCTD14 gene is located on human chromosome 11, a region associated with various genetic disorders, including Jervell and Lange-Nielsen syndrome and Jacobsen syndrome, highlighting KCTD14′s importance in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
KCTD14 Antibody (A-6) References:
- The 11q terminal deletion disorder: a prospective study of 110 cases. | Grossfeld, PD., et al. 2004. Am J Med Genet A. 129A: 51-61. PMID: 15266616
- Towards a proteome-scale map of the human protein-protein interaction network. | Rual, JF., et al. 2005. Nature. 437: 1173-8. PMID: 16189514
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. | Kimura, K., et al. 2006. Genome Res. 16: 55-65. PMID: 16344560
- Human chromosome 11 DNA sequence and analysis including novel gene identification. | Taylor, TD., et al. 2006. Nature. 440: 497-500. PMID: 16554811
- Targeted disruption of the mouse testis-enriched gene Znf230 does not affect spermatogenesis or fertility. | Liu, Y., et al. 2014. Genet Mol Biol. 37: 708-15. PMID: 25505846
- Network meta-analysis of transcriptome expression changes in different manifestations of dengue virus infection. | Winter, C., et al. 2022. BMC Genomics. 23: 165. PMID: 35220956
- A novel DNA methylation-related gene signature for the prediction of overall survival and immune characteristics of ovarian cancer patients. | Wang, S., et al. 2023. J Ovarian Res. 16: 62. PMID: 36978087
- Unraveling potential gene biomarkers for dengue infection through RNA sequencing. | Suppiah, J., et al. 2025. Virus Genes. 61: 26-37. PMID: 39397194
- Hormonally-regulated KCTD14 Expression Is Higher in Oocytes from Antral Follicles Compared to Those from Preantral Follicles in Mice, with Implications in Fertility. | Berkel, C. 2025. Reprod Sci.. PMID: 40044995
- The BTB domain, found primarily in zinc finger proteins, defines an evolutionarily conserved family that includes several developmentally regulated genes in Drosophila. | Zollman, S., et al. 1994. Proc Natl Acad Sci U S A. 91: 10717-21. PMID: 7938017
- The POZ domain: a conserved protein-protein interaction motif. | Bardwell, VJ. and Treisman, R. 1994. Genes Dev. 8: 1664-77. PMID: 7958847
- Crystal structure of the BTB domain from PLZF. | Ahmad, KF., et al. 1998. Proc Natl Acad Sci U S A. 95: 12123-8. PMID: 9770450
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KCTD14 Antibody (A-6) | sc-393876 | 200 µg/ml | $322.00 | |||
KCTD14 Antibody (A-6): m-IgG Fc BP-HRP Bundle | sc-530615 | 200 µg Ab; 10 µg BP | $361.00 | |||
KCTD14 Antibody (A-6): m-IgGκ BP-HRP Bundle | sc-524129 | 200 µg Ab, 40 µg BP | $361.00 | |||
KCTD14 Antibody (A-6): m-IgG2b BP-HRP Bundle | sc-550206 | 200 µg Ab; 10 µg BP | $361.00 | |||
KCTD14 Antibody (A-6) AC | sc-393876 AC | 500 µg/ml, 25% agarose | $424.00 | |||
KCTD14 Antibody (A-6) HRP | sc-393876 HRP | 200 µg/ml | $322.00 | |||
KCTD14 Antibody (A-6) FITC | sc-393876 FITC | 200 µg/ml | $336.00 | |||
KCTD14 Antibody (A-6) PE | sc-393876 PE | 200 µg/ml | $349.00 | |||
KCTD14 Antibody (A-6) Alexa Fluor® 488 | sc-393876 AF488 | 200 µg/ml | $364.00 | |||
KCTD14 Antibody (A-6) Alexa Fluor® 546 | sc-393876 AF546 | 200 µg/ml | $364.00 | |||
KCTD14 Antibody (A-6) Alexa Fluor® 594 | sc-393876 AF594 | 200 µg/ml | $364.00 | |||
KCTD14 Antibody (A-6) Alexa Fluor® 647 | sc-393876 AF647 | 200 µg/ml | $364.00 | |||
KCTD14 Antibody (A-6) Alexa Fluor® 680 | sc-393876 AF680 | 200 µg/ml | $364.00 | |||
KCTD14 Antibody (A-6) Alexa Fluor® 790 | sc-393876 AF790 | 200 µg/ml | $364.00 | |||
KCTD14 (A-6) Neutralizing Peptide | sc-393876 P | 100 µg/0.5 ml | $69.00 |