Integrin αIIb/ITGA2B/CD41 Antibody (B-9): sc-365938

Integrin αIIb Antibody (B-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects Integrin alpha IIb protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-Integrin alpha IIb antibody (B-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Integrin alpha IIb protein plays a crucial role in platelet aggregation and is essential for hemostasis, as Integrin alpha IIb forms a heterodimer with Integrin beta 3 to create the glycoprotein IIb/IIIa complex, which binds fibrinogen and other ligands. This interaction is vital for the formation of stable platelet clots, making Integrin alpha IIb a key player in wound healing and cardiovascular health. Dysregulation of Integrin alpha IIb can lead to bleeding disorders or thrombotic diseases, highlighting Integrin alpha IIb′s importance in both normal physiology and pathological conditions. Integrin alpha IIb monoclonal antibody (B-9) is an invaluable tool for researchers studying integrin-mediated signaling pathways, platelet function, and related diseases, providing insights into the mechanisms of cell adhesion and migration.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Integrin αIIb/ITGA2B/CD41 Antibody (B-9) has 10 citations in a variety of scientific publications.

Primary antibodies like Anti-Integrin αIIb/ITGA2B/CD41 Antibody (B-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Integrin αIIb/ITGA2B/CD41 Antibody (B-9) Specifications

Alternate Product Name: Integrin αIIb

Product Clone Name: B-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 1011-1039

Epitope Target: Integrin αIIb

Epitope Species: human

Product Reactivity/Detection: Integrin αIIb light chain

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 10 citations in various scientific publications

Available Conjugates/Forms for Integrin αIIb/ITGA2B/CD41 Antibody (B-9): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred Integrin αIIb/ITGA2B/CD41 antibody is Integrin αIIb/ITGA2B/CD41 Antibody (MWReg30): sc-19963.