Date published: 2025-12-5

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Integrin alpha IIb Inhibitors

Santa Cruz Biotechnology now offers a broad range of Integrin alpha IIb inhibitors for use in various applications. These inhibitors are crucial in the field of cell biology and biochemistry, playing a significant role in understanding cell adhesion and signaling pathways. Integrin alpha IIb, primarily expressed in platelets, is a key component of the integrin family involved in mediating cell-to-cell and cell-to-extracellular matrix interactions. Inhibitors targeting this integrin are valuable tools for dissecting the molecular mechanisms underlying platelet aggregation and thrombosis. The use of these inhibitors in research enables scientists to study the regulation of integrin function, explore signal transduction pathways, and investigate the role of integrins in various physiological and pathological processes. Additionally, these inhibitors are instrumental in the development of new techniques for studying cell surface interactions and in the design of experiments that require precise modulation of integrin activity. By providing a detailed understanding of integrin-mediated processes, these inhibitors contribute to advancements in areas such as cell migration, immune response, and tissue development. View detailed information on our available Integrin alpha IIb inhibitors by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Eptifibatide acetate

881997-86-0sc-205675
sc-205675A
sc-205675B
5 mg
10 mg
50 mg
$51.00
$109.00
$257.00
5
(1)

Eptifibatide acetate functions as a potent antagonist of integrin alpha IIb, disrupting the fibrinogen binding necessary for platelet aggregation. Its unique structure allows for high specificity in binding, effectively blocking the conformational changes required for integrin activation. This inhibition alters the dynamics of platelet signaling pathways, impacting cellular adhesion and migration. The compound's interaction with integrins showcases its role in modulating cellular responses through competitive inhibition.

E7820

289483-69-8sc-507333
10 mg
$102.00
(0)

GR 144053 trihydrochloride

1215333-48-4sc-361192
sc-361192A
10 mg
50 mg
$116.00
$660.00
3
(0)

GR 144053 trihydrochloride acts as a selective modulator of integrin alpha IIb, influencing the molecular interactions that govern platelet function. Its unique binding affinity alters the conformational landscape of integrin complexes, thereby affecting downstream signaling cascades. The compound's kinetic profile reveals a rapid onset of action, with distinct competitive binding characteristics that modify cellular adhesion dynamics. This specificity highlights its role in fine-tuning integrin-mediated processes.

Cilengitide

188968-51-6sc-507335
5 mg
$215.00
(0)

Tirofiban-d6

144494-65-5 (unlabeled)sc-475655
1 mg
$450.00
(0)

Reversible antagonist of αIIbβ3, inhibiting platelet aggregation.

Picotamide

32828-81-2sc-201334
sc-201334A
10 mg
50 mg
$92.00
$366.00
1
(1)

Inhibits thromboxane A2 formation and αIIbβ3 activation.