
HDAC2 Antibody (B-2) is a mouse monoclonal IgG1 antibody that detects HDAC2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HDAC2, or Histone Deacetylase 2, plays a crucial role in the regulation of gene expression by removing acetyl groups from lysine residues on histone proteins, leading to chromatin condensation and transcriptional repression. This function is vital for maintaining cellular homeostasis and regulating processes such as cell cycle progression, differentiation, and apoptosis. Dysregulation of HDAC2 has been implicated in various diseases, including cancer, where overexpression can lead to silencing of tumor suppressor genes. Additionally, HDAC2 interacts with several key proteins, including transcriptional co-repressor Sin3A and NuRD complex, which further underscores HDAC2′s importance in epigenetic regulation of gene expression. Anti-HDAC2 antibody (B-2) effectively targets this crucial protein, making HDAC2 (B-2) antibody an invaluable tool for researchers studying gene regulation mechanisms and potential therapeutic implications of HDAC inhibition in disease contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Histone Deacetylase 2 (HDAC2) Antibody (B-2) | sc-55541 | 200 µg/ml | $322.00 | |||
Histone Deacetylase 2 (HDAC2) Antibody (B-2): m-IgG Fc BP-HRP Bundle | sc-537068 | 200 µg Ab; 10 µg BP | $361.00 | |||
Histone Deacetylase 2 (HDAC2) Antibody (B-2): m-IgGκ BP-HRP Bundle | sc-534254 | 200 µg Ab; 40 µg BP | $361.00 | |||
Histone Deacetylase 2 (HDAC2) Antibody (B-2): m-IgG1 BP-HRP Bundle | sc-544985 | 200 µg Ab; 20 µg BP | $361.00 |