Date published: 2026-5-6

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Histone Deacetylase 2 (HDAC2) Antibody (B-2): sc-55541

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Datasheets
  • Histone Deacetylase 2 (HDAC2) Antibody (B-2) is a mouse monoclonal IgG1 κ, cited in 7 publications, provided at 200 µg/ml
  • recommended for detection of HDAC2 of mouse, rat and human origin by WB, IP, IF and ELISA
  • See Histone Deacetylase 2 (C-8): sc-9959 for Histone Deacetylase 2 (HDAC2) antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Histone Deacetylase 2 (HDAC2) Antibody (B-2) for WB applications. These reagents are now offered in bundles with Histone Deacetylase 2 (HDAC2) Antibody (B-2) (see ordering information below).
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HDAC2 Antibody (B-2) is a mouse monoclonal IgG1 antibody that detects HDAC2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). HDAC2, or Histone Deacetylase 2, plays a crucial role in the regulation of gene expression by removing acetyl groups from lysine residues on histone proteins, leading to chromatin condensation and transcriptional repression. This function is vital for maintaining cellular homeostasis and regulating processes such as cell cycle progression, differentiation, and apoptosis. Dysregulation of HDAC2 has been implicated in various diseases, including cancer, where overexpression can lead to silencing of tumor suppressor genes. Additionally, HDAC2 interacts with several key proteins, including transcriptional co-repressor Sin3A and NuRD complex, which further underscores HDAC2′s importance in epigenetic regulation of gene expression. Anti-HDAC2 antibody (B-2) effectively targets this crucial protein, making HDAC2 (B-2) antibody an invaluable tool for researchers studying gene regulation mechanisms and potential therapeutic implications of HDAC inhibition in disease contexts.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Histone Deacetylase 2 (HDAC2) Antibody (B-2)

sc-55541
200 µg/ml
$322.00

Histone Deacetylase 2 (HDAC2) Antibody (B-2): m-IgG Fc BP-HRP Bundle

sc-537068
200 µg Ab; 10 µg BP
$361.00

Histone Deacetylase 2 (HDAC2) Antibody (B-2): m-IgGκ BP-HRP Bundle

sc-534254
200 µg Ab; 40 µg BP
$361.00

Histone Deacetylase 2 (HDAC2) Antibody (B-2): m-IgG1 BP-HRP Bundle

sc-544985
200 µg Ab; 20 µg BP
$361.00

What is the recommended fixation method for immunofluorescence staining with HDAC2 (B-2): sc-55541 monoclonal antibody?

Asked by: TinTin
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-24
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Rated 4 out of 5 by from Publication using the antibody in IP andPublication using the antibody in IP and WB with skeletal samples -SCBT Publication Review -SCBT Publication Review
Date published: 2015-04-15
Rated 4 out of 5 by from Signal via w estern blot analysis of HDAC2Signal via w estern blot analysis of HDAC2 expression in Jurkat and NIH/3T3 nuclear extracts. -SCBT QC
Date published: 2015-02-26
Rated 4 out of 5 by from Strong nuclear localization via immunofluorescenceStrong nuclear localization via immunofluorescence staining of methanol-fixed HeLa cells -SCBT QC
Date published: 2015-02-16
Rated 4 out of 5 by from Publication using antibody in CoIP and WBPublication using antibody in CoIP and WB with LNCaP cells -SCBT Publication Review
Date published: 2013-07-30
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Histone Deacetylase 2 (HDAC2) Antibody (B-2) is rated 4.0 out of 5 by 4.
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