Date published: 2026-3-5

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HDAC1 Antibodies

Santa Cruz Biotechnology features a diverse variety of HDAC1 monoclonal antibodies for investigating histone deacetylase 1 (HDAC1) in various biological processes. Multiple detection methods are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HDAC1 is a crucial enzyme involved in the regulation of gene expression through the removal of acetyl groups from histones, leading to chromatin condensation and transcriptional repression. HDAC1 dysregulation has been implicated in numerous diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases, making it a significant target for therapeutic intervention. Understanding HDAC1 function and regulation is essential for elucidating its role in cellular processes and disease mechanisms. Researchers can explore HDAC1 expression patterns across different cell types and tissues using various conjugated formats, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC). HDAC1 research continues to reveal new insights into epigenetic regulation and its impact on gene expression. HDAC1 studies have highlighted its importance in cell cycle regulation, DNA damage response, and cellular differentiation. Santa Cruz Biotechnology monoclonal antibodies for HDAC1 enable researchers worldwide to advance our understanding of epigenetic regulation and its implications in human health and disease.

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HDAC1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Histone Deacetylase 1 Antibody (10E2)

sc-81598mouse IgG1 κ467-482 (h)WB, IP, IF, IHC(P), ELISAm, r, h
160
(36)

Histone Deacetylase 1 Antibody (H-11)

sc-8410mouse IgG1 κ432-482 (h)WB, IP, IF, FCM, ELISAm, r, h
97
(13)

HDAC1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Histone Deacetylase 1 (HDAC1) CRISPR/Cas9 KO Plasmid (h)

sc-400203hGene KnockoutGFP0
(1)

Histone Deacetylase 1 (HDAC1) HDR Plasmid (h)

sc-400203-HDRhHomology Directed RepairPuromycin0
(1)

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (h)

sc-400203-NIChGene KnockoutPuromycin0
(1)

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (h2)

sc-400203-NIC-2hGene KnockoutPuromycin0
(1)

Histone Deacetylase 1 (HDAC1) CRISPR/Cas9 KO Plasmid (m)

sc-436647mGene KnockoutGFP
1
(0)

Histone Deacetylase 1 (HDAC1) HDR Plasmid (m)

sc-436647-HDRmHomology Directed RepairPuromycin
1
(0)

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (m)

sc-436647-NICmGene KnockoutPuromycin
1
(0)

Histone Deacetylase 1 (HDAC1) Double Nickase Plasmid (m2)

sc-436647-NIC-2mGene KnockoutPuromycin
1
(0)

HDAC1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Histone Deacetylase 1 (HDAC1) CRISPR Activation Plasmid (h)

sc-400203-ACThGene ActivationPuro, Blast, Hygro0
(1)

Histone Deacetylase 1 (HDAC1) CRISPR Activation Plasmid (m)

sc-436647-ACTmGene ActivationPuro, Blast, Hygro
1
(0)

Histone Deacetylase 1 (HDAC1) CRISPR Activation Plasmid (m2)

sc-436647-ACT-2mGene ActivationPuro, Blast, Hygro
1
(0)

Histone Deacetylase 1 (HDAC1) Lentiviral Activation Particles (m)

sc-436647-LACmGene ActivationPuro, Blast, Hygro
1
(0)

Histone Deacetylase 1 (HDAC1) Lentiviral Activation Particles (m2)

sc-436647-LAC-2mGene ActivationPuro, Blast, Hygro
1
(0)

HDAC1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Histone Deacetylase 1 (HDAC1) siRNA (h)

sc-29343hGene SilencingN/A
39
(0)

Histone Deacetylase 1 (HDAC1) siRNA (h2)

sc-44208hGene SilencingN/A
2
(0)

Histone Deacetylase 1 (HDAC1) shRNA Plasmid (h)

sc-29343-SHhGene SilencingPuromycin
39
(0)

Histone Deacetylase 1 (HDAC1) shRNA Plasmid (h2)

sc-44208-SHhGene SilencingPuromycin
2
(0)

Histone Deacetylase 1 (HDAC1) shRNA (h) Lentiviral Particles

sc-29343-VhGene SilencingPuromycin
39
(0)

Histone Deacetylase 1 (HDAC1) shRNA (h2) Lentiviral Particles

sc-44208-VhGene SilencingPuromycin
2
(0)

Histone Deacetylase 1 (HDAC1) siRNA (m)

sc-29344mGene SilencingN/A
13
(1)

Histone Deacetylase 1 (HDAC1) shRNA Plasmid (m)

sc-29344-SHmGene SilencingPuromycin
13
(1)

Histone Deacetylase 1 (HDAC1) shRNA (m) Lentiviral Particles

sc-29344-VmGene SilencingPuromycin
13
(1)

Histone Deacetylase 1 (HDAC1) siRNA (r)

sc-270070rGene SilencingN/A
4
(0)

Histone Deacetylase 1 (HDAC1) shRNA Plasmid (r)

sc-270070-SHrGene SilencingPuromycin
4
(0)

Histone Deacetylase 1 (HDAC1) shRNA (r) Lentiviral Particles

sc-270070-VrGene SilencingPuromycin
4
(0)