HDAC1 Inhibitors
Santa Cruz Biotechnology now offers a broad range of HDAC1 Inhibitors. Histone deacetylase proteins (HDACs) are a class of enzymes that remove acetyl groups (O=C-CH3) from an <ε>-N-acetyl lysine amino acid on a histone, allowing histones to wrap DNA more tightly. The deacetylation of histones is associated with transcriptional silencing. Histone deacetylase inhibitors (HDIs) have a long history of use in psychiatry and neurology as mood stabilizers and anti-epileptic. HDIs are studied as a treatment for neurodegenerative diseases and have a potential for cancer therapy. HDAC1 Inhibitors offered by Santa Cruz inhibit HDAC1 and, in some cases, other chromatin remodeling and transcription regulation related proteins. View detailed HDAC1 Inhibitor specifications, including HDAC1 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
Items 1 to 10 of 27 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Valproic acid sodium salt | 1069-66-5 | sc-202378A sc-202378 sc-202378B sc-202378C | 1 g 5 g 25 g 100 g | $21.00 $36.00 $128.00 $362.00 | 9 | |
Valproic acid sodium salt (CAS 1069-66-5) acts as an inhibitor of HDAC1, affecting key cellular processes associated with this enzyme. Its inhibitory role in relation to HDAC1 has broad effects on various cellular activities. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $88.00 $208.00 | 24 | |
MS-275 targets HDAC1's active site, disrupting its deacetylase activity and affecting gene transcription through histone acetylation. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Vorinostat binds to the catalytic domain of HDAC1, inhibiting its deacetylase activity, leading to accumulation of acetylated histones and altered gene expression. | ||||||
Parthenolide | 20554-84-1 | sc-3523 sc-3523A | 50 mg 250 mg | $79.00 $300.00 | 32 | |
Parthenolide (CAS 20554-84-1) is a compound known for inhibiting HDAC1, a protein involved in gene regulation. It affects cellular processes through its interaction with HDAC1, influencing epigenetic modifications without therapeutic implications. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A (CAS 58880-19-6) is a compound that effectively inhibits HDAC1, a protein contributing to gene regulation. It modulates cellular processes via HDAC1 interaction, impacting epigenetic mechanisms without therapeutic connotations. | ||||||
4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide | 193551-00-7 | sc-223859 sc-223859A sc-223859B sc-223859C sc-223859D | 1 mg 5 mg 10 mg 25 mg 60 mg | $38.00 $152.00 $267.00 $576.00 $1229.00 | 5 | |
The compound 4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide (CAS 193551-00-7) functions as an HDAC1 inhibitor. By interacting with HDAC1, it influences gene regulation processes at the cellular level, affecting epigenetic mechanisms without therapeutic connotations. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $63.00 $179.00 | 11 | |
Scriptaid inhibits HDAC1 activity by binding to its active site, causing histone hyperacetylation and altering gene expression patterns. | ||||||
Belinostat | 414864-00-9 | sc-269851 sc-269851A | 10 mg 100 mg | $153.00 $561.00 | ||
Belinostat inhibits HDAC1 by interacting with its catalytic domain, resulting in increased histone acetylation and gene expression modulation. | ||||||
Suberoyl bis-hydroxamic Acid | 38937-66-5 | sc-200887 sc-200887A | 100 mg 500 mg | $50.00 $104.00 | ||
Suberoyl bis-hydroxamic Acid (CAS 38937-66-5) functions as an HDAC1 inhibitor, affecting gene regulation processes within cells. Through its interaction with HDAC1, it modulates epigenetic mechanisms without implications beyond cellular functions. | ||||||
1-Naphthohydroxamic Acid | 6953-61-3 | sc-364388 sc-364388A | 5 mg 25 mg | $85.00 $330.00 | ||
1-Naphthohydroxamic Acid (CAS 6953-61-3) serves as an HDAC1 inhibitor, influencing cellular gene regulation processes. Its interaction with HDAC1 leads to modulation of epigenetic mechanisms, with effects limited to cellular functions. | ||||||