FIR Antibody (B-5): sc-398785
- FIR Antibody (B-5) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 260-559 mapping at the C-terminus of FIR of human origin
- recommended for detection of FIR of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for FIR Antibody (B-5) for WB applications. These reagents are now offered in bundles with FIR Antibody (B-5) (see ordering information below).
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FIR Antibody (B-5) is a mouse monoclonal IgG2b light chain antibody that detects FIR in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). FIR, or FBP interacting repressor, plays a crucial role in regulating the expression of the c-myc gene by interacting with the FUSE-binding protein, which is essential for c-myc activation. This regulation is vital because c-myc is a key player in cell proliferation and growth, and its dysregulation can lead to oncogenesis. FIR is predominantly expressed in various tissues, including the spleen, thymus, prostate, small intestine, colon, and peripheral blood leukocytes, with particularly high levels found in the testis and ovary, indicating potential involvement in reproductive biology. Anti-FIR antibody (B-5) provides reliable detection of this important protein, facilitating research into its role in gene regulation and implications in cancer biology and other diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
FIR Antibody (B-5) | sc-398785 | 200 µg/ml | $322.00 | |||
FIR Antibody (B-5): m-IgG Fc BP-HRP Bundle | sc-538523 | 200 µg Ab; 10 µg BP | $361.00 | |||
FIR Antibody (B-5): m-IgGκ BP-HRP Bundle | sc-536151 | 200 µg Ab; 40 µg BP | $361.00 | |||
FIR Antibody (B-5): m-IgG2b BP-HRP Bundle | sc-549955 | 200 µg Ab; 10 µg BP | $361.00 |