Date published: 2025-10-15

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FIR Inhibitors

FIR inhibitors belong to a distinct chemical class known for their unique ability to modulate certain biological processes. These inhibitors are characterized by their specific interaction with specific molecular targets within cells, eliciting a cascade of molecular events that result in the alteration of cellular functions. The mechanism of action involves the binding of FIR inhibitors to specific protein sites, triggering conformational changes that subsequently disrupt or impede the normal progression of biochemical pathways.

This interference can lead to a myriad of effects, influencing cellular responses, signal transduction, or metabolic pathways. Researchers have been keenly interested in the development and study of FIR inhibitors due to unveil insights into cellular processes and unravel complex molecular interactions. The exploration of these inhibitors offers a fascinating avenue for scientific inquiry into the intricate mechanisms governing cellular activities, holding promise for future advancements in understanding fundamental biological principles.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Pirfenidone

53179-13-8sc-203663
sc-203663A
10 mg
50 mg
$100.00
$408.00
6
(1)

pirfenidone is believed to work by reducing the production of various growth factors and cytokines involved in fibrosis.

BIBF1120

656247-17-5sc-364433
sc-364433A
5 mg
10 mg
$180.00
$315.00
2
(0)

nintedanib targets multiple pathways involved in fibrosis, such as platelet-derived growth factor (PDGF) and fibroblast growth factor (FGF) signaling.

LY2157299

700874-72-2sc-391123
sc-391123A
5 mg
10 mg
$209.00
$352.00
3
(1)

LY2157299 is a potent TGF β RI inhibitor

TD-139

1450824-22-2sc-507553
5 mg
$739.00
(0)

This compound inhibits the action of chitinase-3-like protein 1 (YKL-40), which is implicated in fibrotic diseases. TD139 may help reduce fibrosis by modulating inflammation and tissue remodeling.

2-(2-Chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione

sc-501137
25 mg
$380.00
(0)

This is a dual NADPH oxidase (NOX) 1/4 inhibitor that aims to reduce oxidative stress and inflammation, factors contributing to fibrosis.