EWS Antibody (B-1): sc-398318
- EWS Antibody (B-1) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 628-656 at the C-terminus of EWS of human origin
- recommended for detection of EWS of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- See EWS (G-5): sc-28327 for EWS antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for EWS Antibody (B-1) for WB applications. These reagents are now offered in bundles with EWS Antibody (B-1) (see ordering information below).
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SEE ALSO...
EWS Antibody (B-1) is a mouse monoclonal IgG2b antibody that detects EWS in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). EWS is a crucial nuclear RNA-binding protein that plays a significant role in gene regulation and cellular processes. EWS′s importance is underscored by involvement in various neoplasias, particularly in the Ewing family of tumors, where EWS gene undergoes chromosomal translocation, resulting in fusion with several transcription factors, including ATF-1. The EWS/Fli-1 chimeric protein, formed from the fusion of EWS with the DNA-binding domain of Fli-1, acts as a potent transcriptional activator, significantly enhancing the transcription of target genes and promoting cell transformation. This aberrant activity is linked to tumorigenesis, making EWS a critical target for cancer research. Anti-EWS antibody (B-1) provides a reliable tool for studying the expression and function of EWS, facilitating insights into cancer biology and potential therapeutic interventions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
EWS Antibody (B-1) | sc-398318 | 200 µg/ml | $322.00 | |||
EWS Antibody (B-1): m-IgG Fc BP-HRP Bundle | sc-538416 | 200 µg Ab; 10 µg BP | $361.00 | |||
EWS Antibody (B-1): m-IgGκ BP-HRP Bundle | sc-536027 | 200 µg Ab; 40 µg BP | $361.00 | |||
EWS Antibody (B-1): m-IgG2b BP-HRP Bundle | sc-549946 | 200 µg Ab; 10 µg BP | $361.00 | |||
EWS (B-1) Neutralizing Peptide | sc-398318 P | 100 µg/0.5 ml | $69.00 |