CTLA-4 Antibody (1B8): sc-18829
- CTLA-4 Antibody (1B8) is a Armenian hamster monoclonal IgG provided at 200 µg/ml
- raised against against the extracellular portion of murine CTLA-4 fused to murine IgG2a
- recommended for detection of CTLA-4 of mouse origin by IP, IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also provided azide-free for inhibiting the interaction of CTLA-4 positive cells with the B7 antigen on activated B cells, sc-18829 L, 200 µg/0.1 ml
- See CTLA-4 (F-8): sc-376016 for CTLA-4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CTLA-4 Antibody (1B8). This work is in progress.
QUICK LINKS
CTLA-4 Antibody (1B8) is a Armenian hamster monoclonal IgG antibody engineered to target the extracellular domain of murine CTLA-4, also known as CD152. CTLA-4 is a pivotal immune checkpoint protein that plays a critical role in regulating T cell activation by competing with the costimulatory receptor CD28 for binding to B7 ligands (CD80/CD86) on antigen-presenting cells. This interaction is essential for maintaining immune homeostasis and preventing excessive immune responses that could lead to autoimmunity. CTLA-4 (1B8) antibody effectively modulates immune responses, making CTLA-4 (1B8) monoclonal antibody an invaluable tool for researchers studying T cell regulation and immune-related pathways. CTLA-4 (1B8) antibody demonstrates strong reactivity with mouse CTLA-4 in various applications, including immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). The precise epitope recognition of CTLA-4 (1B8) monoclonal antibody ensures reliable and consistent results, facilitating detailed investigations into the mechanisms of T cell inhibition and the therapeutic potential of immune checkpoint modulation. Additionally, anti-CTLA-4 antibody (1B8) is instrumental in advancing research in immunology and cancer therapy, where understanding and manipulating immune checkpoints are crucial for developing effective treatments. CTLA-4 (1B8) monoclonal antibody provides robust performance and specificity, supporting significant advancements in the field of immune regulation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CTLA-4 Antibody (1B8) | sc-18829 | 200 µg/ml | $322.00 | |||
CTLA-4 Antibody (1B8) FITC | sc-18829 FITC | 200 µg/ml | $336.00 | |||
CTLA-4 Antibody (1B8) L | sc-18829 L | 200 µg/0.1 ml | $322.00 | |||
CTLA-4 Antibody (1B8) PE | sc-18829 PE | 200 µg/ml | $349.00 |