Date published: 2026-7-7

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CTLA Antibodies

Santa Cruz Biotechnology features a diverse variety of CTLA Antibodies for research in immunology and cancer biology. CTLA Antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) plays a critical role in regulating immune responses by acting as an inhibitory receptor on T cells. CTLA-4 function is essential for maintaining immune homeostasis and preventing autoimmunity, making it a significant target in cancer immunotherapy. The modulation of CTLA-4 activity has been shown to enhance anti-tumor immunity, highlighting its importance in the development of therapeutic strategies. Researchers can investigate immune checkpoint pathways and their impact on T cell responses using specific monoclonal antibodies. Understanding CTLA-4 signaling mechanisms helps advance knowledge in autoimmune disorders and cancer treatments. Exploring CTLA-4's role in immune regulation continues to reveal new therapeutic possibilities. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of immune checkpoint regulation and contribute to the development of innovative cancer treatments.

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CTLA Antibodies

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CTLA-4 Antibody (F-8)

sc-376016mouse IgG1 κ195-223 (h)WB, IP, IF, IHC(P), ELISAm, r, h
59
(22)

CTLA-4 Antibody (1B8)

sc-18829A. hamster IgGN/AIP, IF, IHC(P), FCMm

new

(2)

CTLA siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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CTLA-2α siRNA (m)

sc-142619mGene SilencingN/A0
(0)

CTLA-2α shRNA Plasmid (m)

sc-142619-SHmGene SilencingPuromycin0
(0)

CTLA-2α shRNA (m) Lentiviral Particles

sc-142619-VmGene SilencingPuromycin0
(0)

CTLA-4 siRNA (h)

sc-42766hGene SilencingN/A
2
(1)

CTLA-4 shRNA Plasmid (h)

sc-42766-SHhGene SilencingPuromycin
2
(1)

CTLA-4 shRNA (h) Lentiviral Particles

sc-42766-VhGene SilencingPuromycin
2
(1)

CTLA-4 siRNA (m)

sc-42767mGene SilencingN/A0
(1)

CTLA-4 shRNA Plasmid (m)

sc-42767-SHmGene SilencingPuromycin0
(1)

CTLA-4 shRNA (m) Lentiviral Particles

sc-42767-VmGene SilencingPuromycin0
(1)

CTLA CRISPR Knockout (KO) and HDR Plasmids

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CTLA-4 CRISPR/Cas9 KO Plasmid (h)

sc-400948Gene Knockouth0
(0)

CTLA-4 HDR Plasmid (h)

sc-400948-HDRHomology Directed Repairh0
(0)

CTLA-4 CRISPR/Cas9 KO Plasmid (m)

sc-419533Gene Knockoutm0
(0)

CTLA-4 HDR Plasmid (m)

sc-419533-HDRHomology Directed Repairm0
(0)

CTLA CRISPR Double Nickase Plasmids

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CTLA-4 Double Nickase Plasmid (h)

sc-400948-NICGene Knockouth0
(0)

CTLA-4 Double Nickase Plasmid (h2)

sc-400948-NIC-2Gene Knockouth0
(0)

CTLA-4 Double Nickase Plasmid (m)

sc-419533-NICGene Knockoutm0
(0)

CTLA CRISPR Activation Plasmids and Lentiviral Particles

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CTLA-4 CRISPR Activation Plasmid (h)

sc-400948-ACTGene Activationh0
(0)

CTLA-4 CRISPR Activation Plasmid (h2)

sc-400948-ACT-2Gene Activationh0
(0)

CTLA-4 Lentiviral Activation Particles (h)

sc-400948-LACGene Activationh0
(0)

CTLA-4 Lentiviral Activation Particles (h2)

sc-400948-LAC-2Gene Activationh0
(0)