



CREM Antibody (A-2) is a mouse monoclonal IgG1 kappa light chain antibody specifically engineered to detect the cAMP response element modulator (CREM). CREM monoclonal antibody (A-2) is raised against the full-length polyhistidine-tagged CREM fusion protein and is effective in various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CREM is a crucial member of the ATF/CREB family of transcription factors, predominantly localized in the nucleus where CREM plays a vital role in regulating gene expression by binding to cAMP response elements in promoter and enhancer regions. The nuclear presence of CREM is essential for controlling transcriptional activity, which influences key biological processes such as spermatogenesis and cellular responses to hormonal signaling. Additionally, CREM interacts with tissue-specific partners to ensure precise regulation of target genes, highlighting the importance of cellular localization. Anti-CREM antibody (A-2) also exhibits reactivity with CREM proteins from rat origin, expanding applicability in comparative studies across species. By enabling accurate detection and localization of CREM within cells, CREM monoclonal antibody (A-2) serves as an invaluable tool for researchers exploring cellular signaling pathways, gene regulation mechanisms, and reproductive biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CREM Antibody (A-2) | sc-377496 | 200 µg/ml | $322.00 | |||
CREM Antibody (A-2): m-IgG Fc BP-HRP Bundle | sc-538047 | 200 µg Ab; 10 µg BP | $361.00 | |||
CREM Antibody (A-2): m-IgGκ BP-HRP Bundle | sc-535573 | 200 µg Ab; 40 µg BP | $361.00 | |||
CREM Antibody (A-2): m-IgG1 BP-HRP Bundle | sc-545499 | 200 µg Ab; 20 µg BP | $361.00 | |||
CREM Antibody (A-2) X | sc-377496 X | 200 µg/0.1 ml | $322.00 |