Cdc26 Antibody (B-6): sc-377338
- Cdc26 Antibody (B-6) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 1-85 representing full length Cdc26 of human origin
- recommended for detection of Cdc26 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgGκ BP-HRP is the preferred secondary detection reagent for Cdc26 Antibody (B-6) for WB applications. This reagent is now offered in a bundle with Cdc26 Antibody (B-6) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Cdc26 Antibody (B-6) is a mouse monoclonal IgG2b antibody that detects Cdc26 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cdc26 plays a crucial role in regulating the anaphase-promoting complex (APC), a vital protein complex that ensures proper cell cycle progression by controlling specific protein degradation, thereby facilitating the transition from metaphase to anaphase during mitosis. The APC is essential for maintaining genomic stability, as APC prevents premature separation of sister chromatids and limits DNA replication to once per cell cycle. Cdc26 stabilizes the APC, enhancing APC function and ensuring correct cell cycle progression. Dysregulation of Cdc26 or the APC can lead to severe consequences, including aneuploidy and cancer, making anti-Cdc26 antibody (B-6) an invaluable tool for researchers investigating cell cycle regulation mechanisms and their implications in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdc26 Antibody (B-6) | sc-377338 | 200 µg/ml | $316.00 | |||
Cdc26 Antibody (B-6): m-IgGκ BP-HRP Bundle | sc-552155 | 200 µg Ab; 40 µg BP | $354.00 |