Date published: 2026-3-10

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Cdc45 Antibodies

Santa Cruz Biotechnology delivers a wide array of Cdc45 monoclonal antibodies for research in cell cycle regulation and DNA replication. Validated applications include western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Cdc45 plays a significant role in the initiation of DNA replication, acting as a part of the pre-replicative complex. The proper function of Cdc45 is essential for maintaining genomic stability and ensuring accurate cell division. Dysregulation of Cdc45 has been implicated in various cancers, highlighting its importance in cancer biology and therapeutic development. Understanding Cdc45's role in cell cycle regulation provides valuable insights into fundamental biological processes. Research using Cdc45 monoclonal antibodies continues to reveal new aspects of DNA replication mechanisms. The high specificity of Santa Cruz Biotechnology monoclonal antibodies enables researchers worldwide to advance scientific understanding of cell cycle dynamics and their implications in disease.

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Cdc45 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Cdc45 Antibody (G-12)

sc-55569mouse IgG3 κ1-300 (h)WB, IP, IF, ELISAm, r, h
24
(9)

Cdc45 Antibody (E-3)

sc-55568mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAm, r, h
4
(2)

Cdc45 CRISPR Knockout, HDR and Double Nickase Plasmids

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Cdc45 CRISPR/Cas9 KO Plasmid (h)

sc-401882hGene KnockoutGFP0
(0)

Cdc45 HDR Plasmid (h)

sc-401882-HDRhHomology Directed RepairPuromycin0
(0)

Cdc45 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Cdc45 CRISPR Activation Plasmid (h)

sc-401882-ACThGene ActivationPuro, Blast, Hygro0
(0)

Cdc45 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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Cdc45 siRNA (h)

sc-35044hGene SilencingN/A
2
(0)

Cdc45 shRNA Plasmid (h)

sc-35044-SHhGene SilencingPuromycin
2
(0)

Cdc45 shRNA (h) Lentiviral Particles

sc-35044-VhGene SilencingPuromycin
2
(0)

Cdc45 siRNA (m)

sc-35045mGene SilencingN/A0
(0)

Cdc45 shRNA Plasmid (m)

sc-35045-SHmGene SilencingPuromycin0
(0)

Cdc45 shRNA (m) Lentiviral Particles

sc-35045-VmGene SilencingPuromycin0
(0)