Cdc45 Antibody (G-12) is a mouse monoclonal IgG3 kappa light chain antibody that detects Cdc45 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-Cdc45 antibody (G-12) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Cdc45 protein plays a crucial role in the initiation of DNA replication, acting as a vital component of the pre-replicative complex. Cdc45 interacts with other essential proteins, such as Cdc6 and the MCM (minichromosome maintenance) complex, to ensure that DNA replication occurs accurately and efficiently. This function is particularly important because errors in DNA replication can lead to genomic instability, which is a hallmark of many cancers. By facilitating the loading of the MCM complex onto DNA, Cdc45 helps to regulate the transition from the G1 phase to the S phase of the cell cycle, thereby ensuring proper cell division and function. Cdc45 (G-12) antibody detection of this critical protein makes it an invaluable tool for researchers studying cell cycle regulation and the mechanisms underlying DNA replication.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Cdc45 Antibody (G-12) | sc-55569 | 200 µg/ml | $316.00 | |||
Cdc45 Antibody (G-12): m-IgGκ BP-HRP Bundle | sc-521020 | 200 µg Ab, 40 µg BP | $354.00 | |||
Cdc45 Antibody (G-12): m-IgG3 BP-HRP Bundle | sc-550331 | 200 µg Ab; 40 µg BP | $354.00 | |||
Cdc45 Antibody (G-12) AC | sc-55569 AC | 500 µg/ml, 25% agarose | $416.00 | |||
Cdc45 Antibody (G-12) HRP | sc-55569 HRP | 200 µg/ml | $316.00 | |||
Cdc45 Antibody (G-12) FITC | sc-55569 FITC | 200 µg/ml | $330.00 | |||
Cdc45 Antibody (G-12) PE | sc-55569 PE | 200 µg/ml | $343.00 | |||
Cdc45 Antibody (G-12) Alexa Fluor® 488 | sc-55569 AF488 | 200 µg/ml | $357.00 | |||
Cdc45 Antibody (G-12) Alexa Fluor® 546 | sc-55569 AF546 | 200 µg/ml | $357.00 | |||
Cdc45 Antibody (G-12) Alexa Fluor® 594 | sc-55569 AF594 | 200 µg/ml | $357.00 | |||
Cdc45 Antibody (G-12) Alexa Fluor® 647 | sc-55569 AF647 | 200 µg/ml | $357.00 | |||
Cdc45 Antibody (G-12) Alexa Fluor® 680 | sc-55569 AF680 | 200 µg/ml | $357.00 | |||
Cdc45 Antibody (G-12) Alexa Fluor® 790 | sc-55569 AF790 | 200 µg/ml | $357.00 |