Cdc26 Activators
Cdc26 Activators refers to a group of chemical compounds that, through their action on various cellular pathways and processes, can indirectly affect the function of Cdc26 within the APC/C complex. These activators are primarily involved in the inhibition or modulation of pathways that either regulate the cell cycle or affect the stability and turnover of proteins involved in cell cycle progression.
Roscovitine and Palbociclib can indirectly necessitate increased activity of Cdc26 as the cell attempts to maintain homeostasis and progress through the cell cycle phases appropriately. Similarly BI 2536 and ZM447439 can disrupt normal cell cycle progression and indirectly affect Cdc26 function as part of the cell's response to maintain ordered cell cycle events.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Apigenin | 520-36-5 | sc-3529 sc-3529A sc-3529B sc-3529C sc-3529D sc-3529E sc-3529F | 5 mg 100 mg 1 g 5 g 25 g 100 g 1 kg | $33.00 $214.00 $734.00 $1151.00 $2348.00 $3127.00 $5208.00 | 22 | |
A flavone that affects various signaling pathways, possibly influencing Cdc26 through modulation of cell cycle regulators. | ||||||
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $94.00 $265.00 | 42 | |
A cyclin-dependent kinase inhibitor that may indirectly affect the activity of APC/C and thus Cdc26 function. | ||||||
BI 2536 | 755038-02-9 | sc-364431 sc-364431A | 5 mg 50 mg | $151.00 $525.00 | 8 | |
A Polo-like kinase 1 inhibitor that can alter cell cycle progression, which might affect Cdc26's role in APC/C activation. | ||||||
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
A GSK-3 beta inhibitor that could influence Wnt signaling, potentially affecting Cdc26 activity indirectly. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $321.00 | ||
A CDK4/6 inhibitor that could lead to changes in cell cycle regulation, possibly implicating Cdc26's function. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
A JNK inhibitor that could affect cell cycle checkpoints and thus indirectly enhance the function of Cdc26. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
An Aurora kinase inhibitor that can interfere with mitotic progression, potentially impacting the activity of Cdc26. | ||||||