CD34 Antibody (1H6) is a mouse monoclonal IgG1 antibody that detects CD34 in canine samples through western blotting (WB) and flow cytometry (FCM) applications. CD34 is a heavily glycosylated, transmembrane glycoprotein that plays a crucial role in the regulation of hematopoiesis and endothelial cell function. CD34 is predominantly expressed on the surface of lymphohematopoietic stem and progenitor cells, as well as small-vessel endothelial cells, embryonic fibroblasts, and certain cells in both fetal and adult nervous tissue. CD34 expression is highest in the most primitive stem cells, gradually diminishing as lineage-committed progenitors undergo differentiation, which underscores CD34′s importance as a marker for identifying and isolating stem cells in research and clinical settings. Additionally, CD34′s cytoplasmic domain contains consensus sites for phosphorylation by activated protein kinase C, along with serine, threonine, and tyrosine phosphorylation sites, which are critical for mediating intracellular signaling pathways that influence cell adhesion, migration, and proliferation. Anti-CD34 antibody (1H6) is an essential tool for researchers studying stem cell biology and vascular development in canine models.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD34 Antibody (1H6) | sc-53511 | 200 µg/ml | $322.00 | |||
CD34 Antibody (1H6): m-IgG Fc BP-HRP Bundle | sc-536977 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD34 Antibody (1H6): m-IgGκ BP-HRP Bundle | sc-534156 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD34 Antibody (1H6) FITC | sc-53511 FITC | 200 µg/ml | $336.00 | |||
CD34 Antibody (1H6) PE | sc-53511 PE | 200 µg/ml | $349.00 |