CD3-ε Antibody (G-5): sc-137096
- CD3-ε Antibody (G-5) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-207 representing full length CD3-ε of human origin
- recommended for detection of CD3-ε of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See CD3-ε (UCH-T1): sc-1179 for CD3-ε antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD3-ε Antibody (G-5). This work is in progress.
CD3-ε Antibody (G-5) is a mouse monoclonal IgG1 antibody that detects CD3-ε in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CD3-ε plays a crucial role in the immune response as a component of the T cell receptor (TCR) complex, which is essential for T cell activation and signaling. Located on the surface of T cells, CD3-ε is part of a multisubunit complex that transmits signals upon recognition of foreign antigens, facilitating the transition of T cells from a resting state to an activated state. CD3-ε, along with associated chains, ensures T cells can effectively respond to pathogens. CD3-ε contains an immunoreceptor tyrosine-based activation motif (ITAM) that is critical for initiating downstream signaling cascades, making CD3-ε a key player in the regulation of T cell responses. Anti-CD3-ε antibody (G-5) serves as an invaluable tool for researchers studying T cell biology and the mechanisms of immune activation, providing insights into both normal immune function and potential therapeutic targets in immunological diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD3-ε Antibody (G-5) | sc-137096 | 200 µg/ml | $322.00 |