Date published: 2026-4-9

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CD3-ζ Antibodies

Santa Cruz Biotechnology offers a broad range of CD3-ζ monoclonal antibodies for research in T cell activation and immune response. CD3-ζ monoclonal antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). CD3-ζ is a critical component of the T cell receptor complex, playing a vital role in T cell signaling and activation. It is essential for the transduction of activation signals, which are crucial for T cell proliferation and differentiation. Understanding CD3-ζ function advances knowledge in immunotherapy development and immune-related disease research. CD3-ζ expression patterns can be effectively monitored across various cell types and tissues. Researchers can track CD3-ζ localization and interactions within cellular compartments. Signal transduction studies benefit from precise detection of CD3-ζ phosphorylation states. Santa Cruz Biotechnology monoclonal antibodies for CD3-ζ enable researchers worldwide to advance our understanding of immune system regulation and potential therapeutic applications.

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CD3-ζ Antibodies

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CD3-ζ Antibody (6B10.2)

sc-1239mouse IgG1 κ89-105 (h)WB, IP, IF, IHC(P), FCMm, r, h
275
(22)

CD3-ζ Antibody (D-4)

sc-374281mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

CD3-ζ Antibody (E-3)

sc-166435mouse IgG3 κ137-163 (h)WB, IP, IF, ELISAm, r, h
8
(5)

CD3-ζ Antibody (3F67)

sc-70617mouse IgG1 κ89-105 (h)WB, IP, IF, IHC(P), FCMm, r, h
1
(1)

CD3-ζ Antibody (F-3)

sc-166275mouse IgG2b κ137-163 (h)WB, IP, IF, ELISAm, r, h
6
(4)

CD3-ζ Antibody (H146-968)

sc-101411A. hamster IgG2151-164 (m)WB, IP, IF, FCM, ELISAm, r, h
3
(1)

Phospho-Specific CD3-ζ Antibodies

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p-CD3-ζ Antibody (C415.9A)

sc-9975mouse IgG1 κ52-163 (h)WB, IP, FCM, ELISAh
17
(8)

p-CD3-ζ Antibody (96.Tyr 111)

sc-135759mouse IgG1 κTyr 111 (h)WB, IP, ELISAm, r, h

new

(1)

CD3-ζ CRISPR Knockout, HDR and Double Nickase Plasmids

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CD3-ζ CRISPR/Cas9 KO Plasmid (h)

sc-400591hGene KnockoutGFP0
(0)

CD3-ζ HDR Plasmid (h)

sc-400591-HDRhHomology Directed RepairPuromycin0
(0)

CD3-ζ Double Nickase Plasmid (h)

sc-400591-NIChGene KnockoutPuromycin0
(0)

CD3-ζ CRISPR Activation Products

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CD3-ζ CRISPR Activation Plasmid (h)

sc-400591-ACThGene ActivationPuro, Blast, Hygro0
(0)

CD3-ζ CRISPR Activation Plasmid (h2)

sc-400591-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

CD3-ζ siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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CD3-ζ siRNA (h)

sc-29245hGene SilencingN/A0
(0)

CD3-ζ shRNA Plasmid (h)

sc-29245-SHhGene SilencingPuromycin0
(0)

CD3-ζ shRNA (h) Lentiviral Particles

sc-29245-VhGene SilencingPuromycin0
(0)

CD3-ζ/η siRNA (m)

sc-42754mGene SilencingN/A0
(0)

CD3-ζ/η shRNA Plasmid (m)

sc-42754-SHmGene SilencingPuromycin0
(0)

CD3-ζ/η shRNA (m) Lentiviral Particles

sc-42754-VmGene SilencingPuromycin0
(0)