CD14 Antibody (TUK4): sc-19588
- CD14 Antibody (TUK4) is a mouse monoclonal IgG2a κ, cited in 11 publications, provided at 200 µg/ml
- raised against tumor cells from a patient suffering leukemia
- recommended for detection of CD14 of human origin by IF and FCM; also reactive with additional species, including and bovine, porcine and canine
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD14 (5A3B11B5): sc-58951 for CD14 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD14 Antibody (TUK4). These reagents are now offered in bundles with CD14 Antibody (TUK4) (see ordering information below).
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CD14 Antibody (TUK4) is a mouse monoclonal IgG2a kappa light chain antibody raised against tumor cells from a patient suffering leukemia, recommended for the detection of CD14 of human origin by immunofluorescence (IF) and flow cytometry (FCM); anti-CD14 antibody (TUK4) is also reactive with additional species including bovine, porcine, and canine. CD14, also known as the monocyte differentiation antigen CD14 or myeloid cell-specific leucine-rich glycoprotein, is a glycosylphosphatidylinositol (GPI)-anchored membrane protein predominantly expressed on the surface of monocytes, macrophages, and neutrophils. Structurally, CD14 is characterized by multiple leucine-rich repeats (LRRs) that form a horseshoe-shaped solenoid structure, which is crucial for its ability to recognize and bind lipopolysaccharide (LPS) and other pathogen-associated molecular patterns (PAMPs). This structural configuration allows CD14 to play a vital role in the innate immune response by facilitating the detection of bacterial components and triggering downstream signaling pathways that lead to cytokine production and immune activation. The importance of CD14′s structure lies in its direct influence on its function in immune surveillance and response to infection. CD14 monoclonal antibody (TUK4) serves as a valuable tool for researchers studying immune responses, infectious diseases, and leukocyte biology across multiple species.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD14 Antibody (TUK4) | sc-19588 | 200 µg/ml | $322.00 | |||
CD14 Antibody (TUK4): m-IgG Fc BP-HRP Bundle | sc-536617 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD14 Antibody (TUK4): m-IgGκ BP-HRP Bundle | sc-533774 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD14 Antibody (TUK4) FITC | sc-19588 FITC | 200 µg/ml | $336.00 | |||
CD14 Antibody (TUK4) PE | sc-19588 PE | 200 µg/ml | $349.00 |