Date published: 2025-11-20

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cathepsin S Antibody (B-12): sc-271573

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Datasheets
  • cathepsin S Antibody (B-12) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 302-331 at the C-terminus of cathepsin S of human origin
  • recommended for detection of cathepsin S of mouse, rat and human origin by WB, IP, IF and ELISA
  • See cathepsin S (E-3): sc-271619 for cathepsin S antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for cathepsin S Antibody (B-12) for WB applications. These reagents are now offered in bundles with cathepsin S Antibody (B-12) (see ordering information below).

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Cathepsin S Antibody (B-12) is a mouse monoclonal IgG2b antibody that detects cathepsin S in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Cathepsin S is a crucial cysteine protease that plays a significant role in the immune response, particularly in the processing of antigens and the regulation of inflammation. This enzyme is primarily located in lysosomes, where cathepsin S is involved in the degradation of extracellular matrix components and the activation of pro-inflammatory cytokines. Proper functioning of cathepsin S is vital for maintaining tissue homeostasis and modulating immune responses, as dysregulation can lead to various pathological conditions, including autoimmune diseases and cancer. Cathepsin S interacts with specific proteins such as cathepsin L and various cytokines, further underscoring cathepsin S importance in cellular signaling pathways and immune regulation. With versatile applications and a critical role in cellular metabolism, anti-cathepsin S antibody (B-12) serves as an essential tool for researchers studying proteolytic processes and immune responses in various biological contexts.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

cathepsin S Antibody (B-12)

sc-271573
200 µg/ml
$316.00

cathepsin S Antibody (B-12): m-IgGκ BP-HRP Bundle

sc-535002
200 µg Ab; 40 µg BP
$354.00

cathepsin S Antibody (B-12): m-IgG2b BP-HRP Bundle

sc-549329
200 µg Ab; 10 µg BP
$354.00

cathepsin S (B-12) Neutralizing Peptide

sc-271573 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-271573 P appropriate for?

Asked by: jenniferc
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-27
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Rated 5 out of 5 by from western blotI detected cathepsin S by western blot recently.It performed good quality at 1:600 dilution,which shows specific band.
Date published: 2018-05-26
Rated 5 out of 5 by from Good specificity and signal strength for WB in UGood specificity and signal strength for WB in U-87 MG and GA-10 whole cell lysates. -SCBT QC
Date published: 2015-04-07
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cathepsin S Antibody (B-12) is rated 5.0 out of 5 by 2.
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