cathepsin S Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Leupeptin hemisulfate | 103476-89-7 | sc-295358 sc-295358A sc-295358D sc-295358E sc-295358B sc-295358C | 5 mg 25 mg 50 mg 100 mg 500 mg 10 mg | $72.00 $145.00 $265.00 $489.00 $1399.00 $99.00 | 19 | |
Leupeptin hemisulfate acts as a potent inhibitor of cathepsin S, showcasing a unique ability to form stable complexes with the enzyme. Its structural features enable specific interactions with the active site, effectively blocking substrate access. The inhibition kinetics reveal a competitive mechanism, where leupeptin's affinity for cathepsin S significantly alters the enzyme's activity profile. This interaction can modulate proteolytic pathways, influencing cellular processes and protein turnover. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $275.00 $928.00 $1543.00 | 14 | |
E-64 is a selective inhibitor of cathepsin S, characterized by its ability to form covalent bonds with the enzyme's active site. This irreversible binding alters the enzyme's conformation, leading to a significant reduction in proteolytic activity. The kinetics of E-64 demonstrate a time-dependent inhibition, which highlights its unique reactivity. Its specificity for cathepsin S allows for targeted modulation of proteolytic pathways, impacting various cellular functions. | ||||||
Z-FA-FMK | 197855-65-5 | sc-201303 sc-201303A | 1 mg 5 mg | $125.00 $365.00 | 19 | |
Z-Phe-Ala-FMK is a synthetic inhibitor that covalently binds to the active site cysteine of Cathepsin S. | ||||||
Caspase Inhibitor, Negative Control | 105637-38-5 | sc-364672 sc-364672A | 1 mg 5 mg | $113.00 $533.00 | ||
Caspase Inhibitor, Negative Control, acts as a competitive antagonist for cathepsin S, engaging in reversible interactions with the enzyme's active site. This dynamic binding alters the enzyme's substrate affinity, effectively modulating its proteolytic function. The inhibitor's unique structural features facilitate selective engagement, influencing reaction kinetics and enabling fine-tuning of cellular signaling pathways. Its behavior underscores the complexity of protease regulation in biological systems. | ||||||
Cathepsin inhibitor peptide | sc-3130 | 1 mg | $115.00 | 1 | ||
Cathepsin inhibitor peptide functions as a selective modulator of cathepsin S activity, characterized by its ability to form stable complexes with the enzyme. This interaction disrupts the enzyme's catalytic efficiency by altering the conformation of the active site, leading to a decrease in substrate turnover. The peptide's specific amino acid sequence enhances its binding affinity, allowing for precise control over proteolytic processes and influencing cellular homeostasis. | ||||||
K777 | 233277-99-1 | sc-507382 | 10 mg | $555.00 | ||
K11777 is a peptidyl vinyl sulfone inhibitor that specifically targets Cathepsin S activity. | ||||||