Annexin IV Antibody (H-2): sc-374254

Annexin IV Antibody (H-2) is a mouse monoclonal IgG2b light chain antibody that detects Annexin IV in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Annexin IV, also known as endonexin, plays a crucial role in regulating chloride ion flux within cells by mediating the activity of calmodulin kinase II (CaMKII), which is essential for various cellular processes including muscle contraction, neurotransmitter release, and cell signaling. The ability of anti-Annexin IV antibody (H-2) to modulate ion channels highlights its importance in maintaining cellular homeostasis and responding to physiological stimuli. Furthermore, the interaction of Annexin IV with other proteins, such as CaMKII, underscores its role in complex signaling pathways that are vital for cellular function. With specific reactivity and versatile applications, Annexin IV monoclonal antibody (H-2) serves as an invaluable tool for researchers studying the intricate roles of calcium-binding proteins in cellular physiology.

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Annexin IV Antibody (H-2) References:

1. Cloning and functional activity of a novel truncated form of annexin IV in mouse macrophages.  |  Sable, CL. and Riches, DW. 1999. Biochem Biophys Res Commun. 258: 162-7. PMID: 10222253
2. Differential lipid specificities of the repeated domains of annexin IV.  |  Sohma, H., et al. 2001. Biochim Biophys Acta. 1546: 205-15. PMID: 11257523
3. Cyclic changes and hormonal regulation of annexin IV mRNA and protein in human endometrium.  |  Ponnampalam, AP. and Rogers, PA. 2006. Mol Hum Reprod. 12: 661-9. PMID: 16954445
4. Crystallization and preliminary X-ray crystallographic studies of human placental annexin IV.  |  Freemont, PS., et al. 1990. J Mol Biol. 216: 219-21. PMID: 2254922
5. In Vitro Study on the Regulation of Annexin IV and VEGF by hCG in the Human Endometrium.  |  Xu, S., et al. 2020. Biochem Res Int. 2020: 8892930. PMID: 33149950
6. Ca(2+)-dependent binding of endonexin (annexin IV) to membranes: analysis of the effects of membrane lipid composition and development of a predictive model for the binding interaction.  |  Junker, M. and Creutz, CE. 1994. Biochemistry. 33: 8930-40. PMID: 8043580
7. Highly polarized expression of carbohydrate-binding protein p33/41 (annexin IV) on the apical plasma membrane of epithelial cells in renal proximal tubules.  |  Kojima, K., et al. 1994. FEBS Lett. 342: 313-8. PMID: 8150091
8. Endonexin (annexin IV)-mediated lateral segregation of phosphatidylglycerol in phosphatidylglycerol/phosphatidylcholine membranes.  |  Junker, M. and Creutz, CE. 1993. Biochemistry. 32: 9968-74. PMID: 8399166
9. Characterization of carbohydrate-binding protein p33/41: relation with annexin IV, molecular basis of the doublet forms (p33 and p41), and modulation of the carbohydrate binding activity by phospholipids.  |  Kojima, K., et al. 1996. J Biol Chem. 271: 7679-85. PMID: 8631806
10. Modulation of cell surface lectin receptors on K562 human erythroleukemia cells induced by transfection with annexin IV cDNA.  |  Satoh, A., et al. 1997. FEBS Lett. 405: 107-10. PMID: 9094435

The preferred Annexin IV antibody is Annexin IV Antibody (D-2): sc-46693.