MOR Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Naloxone hydrochloride | 357-08-4 | sc-203153 sc-203153A sc-203153B sc-203153C | 50 mg 100 mg 1 g 10 g | $87.00 $169.00 $342.00 $1864.00 | 2 | |
Naloxone hydrochloride acts as a competitive antagonist at the mu-opioid receptor (MOR), characterized by its ability to disrupt opioid binding through specific electrostatic interactions. Its unique structural conformation allows for effective steric hindrance, preventing receptor activation. The compound exhibits rapid kinetics, with a high affinity for the MOR, leading to swift displacement of agonists. This dynamic interaction profile highlights its role in modulating receptor signaling and influencing downstream pathways. | ||||||
JTC 801 | 244218-51-7 | sc-203614 sc-203614A | 10 mg 50 mg | $131.00 $582.00 | ||
JTC 801 functions as a mu-opioid receptor (MOR) modulator, exhibiting a distinctive binding affinity that alters receptor conformation. Its unique molecular structure facilitates specific hydrophobic interactions, enhancing its selectivity. The compound's kinetic profile reveals a rapid onset of action, allowing for effective competition against endogenous ligands. Additionally, JTC 801's ability to stabilize receptor states contributes to its nuanced influence on signaling cascades, impacting cellular responses. | ||||||
Nalmefene hydrochloride | 58895-64-0 | sc-361270 sc-361270A sc-361270B sc-361270C sc-361270D | 100 mg 500 mg 1 g 5 g 10 g | $159.00 $296.00 $377.00 $893.00 $1325.00 | ||
Nalmefene hydrochloride acts as a mu-opioid receptor (MOR) antagonist, characterized by its ability to disrupt the typical ligand-receptor interactions. Its structural features promote unique electrostatic interactions, which influence receptor dynamics and alter downstream signaling pathways. The compound exhibits a slow dissociation rate from the receptor, allowing for prolonged modulation of receptor activity. This behavior highlights its potential to fine-tune cellular responses through intricate molecular mechanisms. | ||||||
β-Funaltrexamine hydrochloride | 72786-10-8 | sc-362050 sc-362050A | 2 mg 10 mg | $463.00 $1569.00 | ||
β-Funaltrexamine hydrochloride functions as a selective mu-opioid receptor (MOR) modulator, distinguished by its unique binding affinity and conformational changes upon interaction. Its specific stereochemistry facilitates unique hydrogen bonding and hydrophobic interactions, enhancing receptor selectivity. The compound's kinetic profile reveals a rapid onset of action, coupled with a distinctive allosteric modulation that influences receptor conformation and alters intracellular signaling cascades. | ||||||
Naloxonazine dihydrochloride | 82824-01-9 | sc-203152 | 10 mg | $156.00 | ||
Naloxonazine dihydrochloride acts as a mu-opioid receptor (MOR) antagonist, characterized by its ability to induce specific conformational shifts in the receptor structure. This compound exhibits a unique interaction profile, engaging in electrostatic and van der Waals forces that stabilize its binding. Its kinetic behavior is marked by a prolonged duration of action, allowing for sustained receptor occupancy and modulation of downstream signaling pathways, ultimately influencing cellular responses. | ||||||
Alvimopan | 156053-89-3 | sc-214531 | 10 mg | $340.00 | ||
Alvimopan functions as a mu-opioid receptor (MOR) antagonist, distinguished by its selective binding affinity that alters receptor dynamics. It engages in hydrophobic interactions and hydrogen bonding, facilitating a unique conformational state that disrupts typical opioid signaling. The compound exhibits rapid kinetics, allowing for swift receptor dissociation, which can influence the overall receptor landscape and downstream cellular mechanisms, thereby affecting physiological responses. | ||||||
Met-Enkephalin | 58569-55-4 | sc-391915 | 25 mg | $224.00 | 1 | |
Met-Enkephalin acts as an endogenous mu-opioid receptor (MOR) agonist, characterized by its ability to induce receptor activation through specific peptide interactions. Its structure allows for effective binding via ionic and hydrophobic forces, promoting a conformational shift that enhances signal transduction. The compound's kinetics are notable for their rapid onset, leading to immediate modulation of intracellular pathways, which can significantly impact neuronal excitability and neurotransmitter release. | ||||||