Cytokeratin 8 Inhibitors
Common Cytokeratin 8 Inhibitors include, but are not limited to Withaferin A CAS 5119-48-2, Arsenic(III) oxide CAS 1327-53-3, Rho Kinase Inhibitor IV CAS 913844-45-8, Y-27632 dihydrochloride CAS 129830-38-2 and Dasatinib CAS 302962-49-8.
Cytokeratin 8 inhibitors belong to a chemical class designed to target the activity of the cytokeratin 8 protein. Cytokeratin 8 is a member of the cytokeratin family, which are intermediate filament proteins found in epithelial cells. These proteins provide structural integrity to cells and contribute to various cellular functions, including mechanical support and cell signaling. Cytokeratin 8 is particularly prominent in simple epithelia and is involved in maintaining cell shape, protecting cells from mechanical stress, and participating in cell migration and adhesion processes.
Inhibiting cytokeratin 8 with specific inhibitors allows researchers to explore the functional roles of this protein in cellular processes and tissue dynamics. These inhibitors are utilized as tools to investigate the effects of disrupting cytokeratin 8's function, aiding in the understanding of its contributions to cell mechanics, migration, and tissue organization. By perturbing cytokeratin 8 activity, researchers can delve into the intricate interplay between cellular structure, signaling pathways, and overall tissue integrity, ultimately revealing insights into the complex biology of epithelial tissues.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $130.00 $583.00 $4172.00 $20506.00 | 20 | |
A natural compound with potential inhibitory effects on CK8 expression, potentially affecting cytoskeletal organization and cell migration. | ||||||
Arsenic(III) oxide | 1327-53-3 | sc-210837 sc-210837A | 250 g 1 kg | $89.00 $228.00 | ||
May inhibit CK8 expression and impact cell survival, potentially affecting cancer cell proliferation and apoptosis. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A specific Rho kinase inhibitor that may impact CK8 expression and cytoskeletal organization in cells. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
A kinase inhibitor that could affect CK8 expression, potentially influencing cellular functions in specific contexts. | ||||||
Honokiol | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 4 | |
A natural compound that might impact CK8 expression and cell migration, potentially affecting cancer cell behavior. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A catechin found in green tea with potential effects on CK8 expression, potentially influencing cellular responses. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
A cyclin-dependent kinase inhibitor that could affect CK8 expression and cellular proliferation in specific contexts. | ||||||
PX 12 | 141400-58-0 | sc-358518 sc-358518A | 10 mg 50 mg | $133.00 $505.00 | 9 | |
A thioredoxin-1 inhibitor that might modulate CK8 expression and impact redox regulation in cells. | ||||||
Gallotannin | 1401-55-4 | sc-202619 sc-202619A sc-202619B sc-202619C sc-202619D sc-202619E sc-202619F | 1 g 10 g 100 g 250 g 1 kg 2.5 kg 5 kg | $26.00 $37.00 $67.00 $78.00 $234.00 $536.00 $983.00 | 12 | |
A polyphenolic compound with potential effects on CK8 expression, potentially influencing cellular responses. | ||||||