Date published: 2026-8-1

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Cryopyrin Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of Cryopyrin monoclonal antibodies for research focused on understanding inflammatory responses and immune system regulation. Cryopyrin Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Cryopyrin, also known as NLRP3, functions as a key component of the innate immune system, playing a vital role in inflammation regulation and caspase-1 activation. Dysregulation of Cryopyrin has been implicated in several autoinflammatory diseases, making it an important target for therapeutic intervention and research. Understanding Cryopyrin function is essential for elucidating the mechanisms underlying inflammatory conditions and developing effective treatments. Researchers worldwide utilize Cryopyrin monoclonal antibodies to investigate cellular pathways and molecular mechanisms involved in immune responses. Current studies focus on how Cryopyrin influences inflammation and its potential role in various disease states. Ongoing research with Cryopyrin continues to reveal new insights into immune system regulation and inflammatory processes. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of Cryopyrin's role in health and disease, contributing to the development of new therapeutic strategies.

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Cryopyrin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Cryopyrin/NALP3/NLRP3 Antibody (6F12)

sc-134306mouse IgG2a κN-terminus (h)WB, IP, ELISAh
45
(21)

Cryopyrin/NALP3/NLRP3 Antibody (F-11)

sc-518122mouse IgM κ200-221 (h)WB, IP, IF, ELISAh
1
(1)

Cryopyrin/NALP3/NLRP3 Antibody (H-8)

sc-518123mouse IgG2b κ200-221 (h)WB, IP, IF, ELISAh
5
(2)

Cryopyrin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Cryopyrin/NALP3/NLRP3 siRNA (h)

sc-45469hGene SilencingN/A
39
(1)

Cryopyrin/NALP3/NLRP3 shRNA Plasmid (h)

sc-45469-SHhGene SilencingPuromycin
39
(1)

Cryopyrin/NALP3/NLRP3 shRNA (h) Lentiviral Particles

sc-45469-VhGene SilencingPuromycin
39
(1)

Cryopyrin/NALP3/NLRP3 siRNA (m)

sc-45470mGene SilencingN/A
15
(2)

Cryopyrin/NALP3/NLRP3 shRNA Plasmid (m)

sc-45470-SHmGene SilencingPuromycin
15
(2)

Cryopyrin/NALP3/NLRP3 shRNA (m) Lentiviral Particles

sc-45470-VmGene SilencingPuromycin
15
(2)

Cryopyrin CRISPR Knockout (KO) and HDR Plasmids

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Cryopyrin/NALP3/NLRP3 CRISPR/Cas9 KO Plasmid (h)

sc-400270Gene Knockouth0
(0)

Cryopyrin/NALP3/NLRP3 HDR Plasmid (h)

sc-400270-HDRHomology Directed Repairh0
(0)

Cryopyrin/NALP3/NLRP3 CRISPR/Cas9 KO Plasmid (m)

sc-432122Gene Knockoutm0
(0)

Cryopyrin/NALP3/NLRP3 HDR Plasmid (m)

sc-432122-HDRHomology Directed Repairm0
(0)

Cryopyrin CRISPR Double Nickase Plasmids

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Cryopyrin/NALP3/NLRP3 Double Nickase Plasmid (h)

sc-400270-NICGene Knockouth0
(0)

Cryopyrin/NALP3/NLRP3 Double Nickase Plasmid (h2)

sc-400270-NIC-2Gene Knockouth0
(0)

Cryopyrin/NALP3/NLRP3 Double Nickase Plasmid (m)

sc-432122-NICGene Knockoutm0
(0)

Cryopyrin/NALP3/NLRP3 Double Nickase Plasmid (m2)

sc-432122-NIC-2Gene Knockoutm0
(0)

Cryopyrin CRISPR Activation Plasmids and Lentiviral Particles

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Cryopyrin/NALP3/NLRP3 CRISPR Activation Plasmid (h)

sc-400270-ACTGene Activationh0
(0)

Cryopyrin/NALP3/NLRP3 CRISPR Activation Plasmid (m)

sc-432122-ACTGene Activationm0
(0)

Cryopyrin/NALP3/NLRP3 CRISPR Activation Plasmid (m2)

sc-432122-ACT-2Gene Activationm0
(0)

Cryopyrin/NALP3/NLRP3 Lentiviral Activation Particles (m)

sc-432122-LACGene Activationm0
(0)