Date published: 2026-5-11

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BDNF Activators

BDNF Activators, which stands for Brain-Derived Neurotrophic Factor Activators, represent a class of chemical compounds that have garnered significant attention in the field of neuroscience and neuropharmacology. These compounds are specifically designed to target and enhance the activity of brain-derived neurotrophic factor (BDNF), a critical protein in the central nervous system. BDNF is known for its pivotal role in promoting the survival, growth, and maintenance of neurons, making it a key player in neuroplasticity – the brain's ability to adapt and reorganize its structure and function in response to experiences and environmental changes. BDNF Activators typically work by modulating the signaling pathways associated with BDNF, either by directly stimulating its production or by enhancing its binding to its receptors, such as TrkB. This class of compounds can vary widely in terms of their chemical structures and mechanisms of action.

Some BDNF Activators function as small molecules that can readily penetrate the blood-brain barrier, while others may act through indirect mechanisms, such as promoting the release of BDNF from glial cells or enhancing synaptic activity. Researchers have been keenly interested in understanding how these activators influence neuronal plasticity, as this knowledge may have implications for cognitive enhancement, learning, and memory processes. In summary, BDNF Activators constitute a diverse class of compounds with the common objective of augmenting the activity of brain-derived neurotrophic factor within the central nervous system. Their mechanisms of action can vary, but their ultimate aim is to harness the potential of BDNF in promoting neuronal health and adaptability.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol is a natural compound found in grapes and red wine. It is thought to activate BDNF by increasing the expression of the BDNF gene and promoting neuronal survival.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin is the active component of turmeric. It may activate BDNF by modulating various signaling pathways, reducing inflammation, and enhancing synaptic plasticity.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin is a flavonoid found in fruits and vegetables. It may activate BDNF by enhancing the production of BDNF and promoting its release in the brain.

Hesperidin

520-26-3sc-205711
sc-205711A
25 g
100 g
$82.00
$204.00
5
(1)

Hesperidin is a flavonoid primarily found in citrus fruits. It may activate BDNF by reducing oxidative stress and inflammation, which can indirectly support BDNF expression.

Fisetin

528-48-3sc-276440
sc-276440A
sc-276440B
sc-276440C
sc-276440D
50 mg
100 mg
500 mg
1 g
100 g
$52.00
$79.00
$104.00
$156.00
$2913.00
7
(1)

Fisetin is a naturally occurring flavonoid in strawberries and other fruits. It may activate BDNF by promoting the activation of specific pathways involved in BDNF synthesis.

(−)Epicatechin

490-46-0sc-205672
sc-205672A
1 mg
5 mg
$51.00
$138.00
(1)

Epicatechin is a flavanol found in cocoa and tea. It may activate BDNF by improving blood flow to the brain and promoting neurogenesis (the growth of new neurons).

sn-Glycero-3-phosphocholine

28319-77-9sc-301813
sc-301813A
5 g
25 g
$112.00
$287.00
(1)

sn-Glycero-3-phosphocholine is a choline compound. It may activate BDNF by providing the necessary substrate for acetylcholine synthesis, which supports cognitive function and BDNF release.

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium is an agent in research used in psychiatry. It may activate BDNF by modulating intracellular signaling pathways and promoting the expression of neurotrophic factors.