Date published: 2026-4-24

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UPK1B Activators

UPK1B, also known as uroplakin 1B, holds significance in the domain of urothelial differentiation, particularly within the context of the bladder. The role it plays emphasizes the importance of understanding chemicals that might modulate its activity. All-trans retinoic acid, for instance, possesses the ability to instigate differentiation across varied cell types, suggesting its potential to influence urothelial cell differentiation where UPK1B functions. Further, elements like EGF are directly associated with urothelial cell proliferation, offering a gateway to understand the intricacies of differentiation pathways and their intersection with UPK1B.

Within this realm, chemicals like 5-Aza-2'-deoxycytidine, a DNA methylation inhibitor, are particularly fascinating as they introduce the dimension of epigenetic regulation in cellular differentiation. Another molecule, Phorbol 12-myristate 13-acetate (PMA), is recognized for its ability to modulate both cell differentiation and proliferation, presenting avenues to explore its effects on urothelial differentiation. Hormones like 3,3',5-triiodo-L-thyronine (T3), intricately weave the narrative of cellular processes where UPK1B is a crucial player.

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Induces differentiation in various cell types and can influence urothelial cell differentiation.

L-3,3′,5-Triiodothyronine, free acid

6893-02-3sc-204035
sc-204035A
sc-204035B
10 mg
100 mg
250 mg
$41.00
$77.00
$153.00
(1)

Thyroid hormone involved in numerous cellular processes, including differentiation.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$218.00
$322.00
$426.00
7
(1)

A DNA methylation inhibitor that can induce cellular differentiation in various contexts.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

Influences cell differentiation and proliferation in various systems, might affect urothelial differentiation.

Dibutyryl-cAMP

16980-89-5sc-201567
sc-201567A
sc-201567B
sc-201567C
20 mg
100 mg
500 mg
10 g
$47.00
$136.00
$492.00
$4552.00
74
(7)

cAMP analog that can promote differentiation in certain cell types.

Hydrocortisone

50-23-7sc-300810
5 g
$102.00
6
(1)

Affects differentiation in several cell types, including potential influences on urothelial cells.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Similar to hydrocortisone, it can impact cellular differentiation processes.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Known for its role in differentiation and growth in multiple cell systems.