MTUS2 Activators
MTUS2 activators are compounds that interact with the molecular pathways involving the MTUS2 gene, which encodes for a protein that is implicated in various cellular processes. The MTUS2 gene, also known as Microtubule Associated Scaffold Protein 2, plays a role in the stabilization of microtubules, which are integral components of the cellular cytoskeleton. Microtubules are dynamic structures that are essential for a wide range of cellular functions, including maintaining cell shape, enabling cellular transport, and facilitating cell division. MTUS2 activators influence the activity of proteins encoded by the MTUS2 gene, thereby affecting the microtubule networks within cells. By doing so, they can impact the dynamics of cell architecture and the intracellular distribution of organelles and vesicles.
The chemical nature of MTUS2 activators can be diverse, ranging from small organic molecules to larger biomolecules, each designed to engage with the MTUS2 protein in different ways. The precise mechanism of action of these activators is often complex, involving the modulation of the protein-protein interactions that regulate microtubule stability and function. At the molecular level, MTUS2 activators may bind to the MTUS2 protein or its partners, altering the conformation of these proteins, which can result in enhanced stabilization of microtubules or modification of microtubule dynamics. This modulation is achieved through a delicate balance of promoting or inhibiting the interactions that are crucial for the proper functioning of the microtubule network.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules by binding to β-tubulin and promoting polymerization, preventing depolymerization. This action can result in increased expression of microtubule-associated proteins like MTUS2 to maintain cellular architecture. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Induces microtubule depolymerization, which could trigger a cellular stress response, potentially leading to upregulation of MTUS2 as part of a compensatory mechanism to reinforce the microtubule network. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Acts on sirtuin pathways that regulate cellular stress responses; upregulation of MTUS2 may occur as part of these pathways to maintain microtubule integrity under stress conditions. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Inhibits GSK-3β leading to increased β-catenin activity, which can enhance gene transcription; MTUS2 expression might be upregulated due to changes in gene expression profiles. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Inhibits DNA methyltransferase, causing gene demethylation; this may result in the upregulation of MTUS2 by removing epigenetic silencing marks on the gene. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Inhibits histone deacetylases leading to a more open chromatin structure and potentially increased gene expression; MTUS2 might be upregulated as a result of enhanced transcriptional activity. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Modulates gene expression through nuclear receptors; it may enhance MTUS2 expression by activating retinoic acid-responsive elements in the gene's promoter region. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Activates the vitamin D receptor, which can bind to vitamin D response elements in gene promoters, potentially including that of MTUS2, resulting in increased gene expression. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $130.00 $583.00 $4172.00 $20506.00 | 20 | |
Alters microtubule dynamics by binding to β-tubulin; this disruption may trigger a cellular response that includes upregulation of MTUS2 to combat microtubule destabilization. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Interacts with various signaling molecules and pathways; it can modulate cellular stress pathways, potentially leading to an increase in MTUS2 expression as part of a protective cellular response. | ||||||