MON2, also known as MON2 homolog, is a protein that plays a critical role in vesicle trafficking, a process essential for the transport and exchange of proteins and lipids between different compartments within a cell. The MON2 protein is encoded by the MON2 gene in humans.One key function of MON2 involves endosome-to-Golgi trafficking. The Golgi apparatus serves as a major sorting station within cells, packaging and distributing proteins and lipids to their appropriate destinations. Endosomes are vesicles that transport these substances from the cell membrane to the Golgi. MON2 helps guide this transport, ensuring the proper delivery of these substances.
MON2 is also involved in the regulation of autophagy, a cellular process that degrades and recycles cellular components. In this context, MON2 interacts with the autophagy-related protein ATG9, facilitating the recruitment of ATG9 to autophagosomes.Moreover, MON2 has been implicated in lipid metabolism and the maintenance of lipid droplet morphology. Lipid droplets are the organelles that store neutral lipids, such as triglycerides and cholesterol esters, within cells.Alterations in the function of MON2 can impact vesicle trafficking, lipid metabolism, and autophagy, potentially leading to a variety of cellular dysfunctions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
Bafilomycin A1, a specific inhibitor of V-ATPase, can affect endosomal acidification, potentially influencing MON2-mediated processes. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $89.00 | 44 | |
Dynasore, a dynamin inhibitor, affects endocytosis and vesicle trafficking, which might indirectly impact MON2 function. | ||||||
Monensin A | 17090-79-8 | sc-362032 sc-362032A | 5 mg 25 mg | $155.00 $525.00 | ||
Monensin, an ionophore that disrupts lysosomal and endosomal function, could indirectly influence MON2 activity in membrane trafficking. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Nocodazole, a microtubule polymerization inhibitor, can impact intracellular trafficking, potentially affecting MON2's role. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Cytochalasin D, an inhibitor of actin polymerization, can alter cytoskeletal dynamics, potentially impacting MON2-mediated sorting. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin, a PI3 kinase inhibitor, can affect endosomal trafficking pathways, potentially influencing MON2 activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, might indirectly affect signaling pathways involving MON2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002, another PI3 kinase inhibitor, can influence vesicle trafficking and endosomal processes, potentially impacting MON2. | ||||||
Daclatasvir | 1009119-64-5 | sc-500663 | 100 mg | $330.00 | ||
Pitstop 2, an inhibitor of clathrin-mediated endocytosis, could indirectly affect MON2's function in membrane trafficking. | ||||||
Chlorpromazine | 50-53-3 | sc-357313 sc-357313A | 5 g 25 g | $61.00 $110.00 | 21 | |
Chlorpromazine, known to inhibit clathrin-mediated endocytosis, might have an indirect impact on MON2 activity. | ||||||