INTS7 activators constitute a specialized class of chemical compounds that have garnered attention in the field of molecular biology and cellular processes. These compounds are meticulously designed to modulate the activity of INTS7, a protein-coding gene with essential roles in various cellular functions, particularly in the context of RNA processing and transcriptional regulation. INTS7, also known as Integrator Complex Subunit 7, is a component of the Integrator complex, which plays a crucial role in processing small nuclear RNAs (snRNAs) and assisting in the transcription of RNA polymerase II-dependent genes. INTS7 activators function by targeting specific regulatory elements within the INTS7 gene, often located in promoter or enhancer regions, with the primary objective of enhancing its transcription and subsequent translation into functional protein products.
The mechanisms through which INTS7 activators exert their effects may vary, but their core purpose is to act as molecular switches, amplifying the activity of INTS7. Researchers are continually exploring the potential applications and implications of INTS7 activation, aiming to deepen our understanding of how this gene contributes to cellular processes, particularly within the context of RNA processing and transcriptional regulation. This class of compounds holds promise for advancing our knowledge of gene regulation, specifically within the realm of INTS7 and its roles in maintaining the integrity of RNA processing pathways and supporting efficient gene transcription. INTS7 activators serve as valuable tools in ongoing investigations within molecular biology, offering opportunities to uncover the complex roles that INTS7 may play in cellular functions and its potential impact on various cellular processes related to RNA biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid acts through retinoic acid receptors to regulate gene transcription, potentially affecting INTS7 expression. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylate cyclase, raising cAMP levels, which might upregulate INTS7 via cAMP response element-binding (CREB) proteins. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG can modulate various signaling pathways and transcription factors, potentially influencing INTS7 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is known to interact with multiple signaling pathways that could lead to upregulation of INTS7 expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, an HDAC inhibitor, might enhance INTS7 expression by altering chromatin accessibility. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine influences several intracellular signaling cascades, which could hypothetically increase INTS7 gene expression. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $32.00 $85.00 | 6 | |
Theophylline raises intracellular cAMP levels, potentially enhancing INTS7 expression through cAMP-dependent pathways. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
The active form of vitamin D can modulate gene expression through its receptor, which may include the INTS7 gene. | ||||||
Zebularine | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $129.00 $284.00 $1004.00 | 3 | |
Zebularine is a DNA methyltransferase inhibitor that may cause hypomethylation of the INTS7 gene promoter, enhancing its expression. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Dibutyryl-cAMP is a cAMP analog that can activate PKA and could potentially upregulate INTS7 transcription through CREB. | ||||||