IL-11Rα Activators
The chemical class of IL-11Rα Activators encompasses various compounds that can potentially stimulate or modulate the expression and activity of IL-11Rα. This class includes agents like PMA and Forskolin, which activate specific signaling pathways (PKC and cAMP respectively) and could lead to the upregulation of IL-11Rα.
Glucocorticoids such as Dexamethasone, and active forms of vitamins like 1,25-Dihydroxyvitamin D3, can modulate immune responses and potentially enhance IL-11Rα expression. Compounds known for their anti-inflammatory and immune-modulatory effects, including Curcumin, EGCG, Sulforaphane, Resveratrol, Aspirin, and Sodium Butyrate, are included due to their potential to influence signaling pathways associated with IL-11Rα. Retinoic Acid, involved in cellular differentiation, and essential nutrients like Zinc, also contribute to this class, potentially affecting the expression and function of IL-11Rα.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
A diester of phorbol known to activate protein kinase C (PKC), which can influence various signaling pathways, potentially leading to the upregulation of IL-11Rα. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
An activator of adenylate cyclase, leading to increased cAMP levels and potentially enhancing IL-11Rα expression via cAMP-dependent pathways. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid that can modulate inflammatory pathways and potentially influence IL-11Rα expression. | ||||||
1α,25-Dihydroxyvitamin D3 | 32222-06-3 | sc-202877B sc-202877A sc-202877C sc-202877D sc-202877 | 50 µg 1 mg 5 mg 10 mg 100 µg | $220.00 $645.00 $1000.00 $1500.00 $440.00 | 32 | |
The active form of Vitamin D, which can modulate immune responses and potentially enhance IL-11Rα expression. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Known for its anti-inflammatory properties, curcumin can modulate signaling pathways, potentially leading to enhanced IL-11Rα expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
A major polyphenol in green tea, known for its anti-inflammatory effects, could indirectly activate IL-11Rα by influencing related signaling pathways. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
A compound found in cruciferous vegetables, known to modulate various cellular pathways, potentially affecting IL-11Rα expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
A polyphenol found in grapes, known to modulate a variety of signaling pathways, potentially influencing IL-11Rα activity. | ||||||
Aspirin | 50-78-2 | sc-202471 sc-202471A | 5 g 50 g | $20.00 $42.00 | 4 | |
An anti-inflammatory drug that can modulate cyclooxygenase pathways and potentially affect IL-11Rα expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
A short-chain fatty acid known for its role in gene regulation and inflammation modulation, which could potentially enhance IL-11Rα expression. | ||||||