Date published: 2026-4-23

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Dapper2 Activators

Dapper2 activators constitute a class of chemical compounds designed to modulate the activity of the Dapper2 protein, also known as Dact2 (Dapper/Frodo homolog 2). Dapper2 is a member of the Dapper/Frodo family of proteins, which are involved in various signaling pathways and developmental processes during embryogenesis. These proteins are known for their role as scaffold proteins that interact with other signaling molecules, particularly those associated with the Wnt (Wingless-related integration site) signaling pathway.

Dapper2 activators are specifically engineered to interact with Dapper2 and potentially influence its interactions with other signaling components within the Wnt pathway or related cellular pathways. By targeting Dapper2, these compounds may modulate its role as a scaffold protein, affecting the formation of protein complexes and the regulation of downstream signaling events. The study of Dapper2 activators provides insights into the intricate mechanisms of Wnt signaling and its involvement in various developmental processes and tissue homeostasis. Further research is necessary to elucidate the precise mechanisms of action and the potential biological consequences associated with Dapper2 activation, offering valuable insights into cellular physiology and signaling pathways involved in development and tissue maintenance.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Lithium

7439-93-2sc-252954
50 g
$214.00
(0)

Lithium chloride inhibits GSK-3β and activates the Wnt/beta-catenin pathway. By affecting this pathway, it may influence Dapper2 expression.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$110.00
$250.00
$936.00
$50.00
33
(2)

Quercetin has been reported to inhibit the Wnt/beta-catenin pathway, which might influence Dapper2 expression.

Sulindac

38194-50-2sc-202823
sc-202823A
sc-202823B
1 g
5 g
10 g
$32.00
$86.00
$150.00
3
(1)

Sulindac has been shown to inhibit the Wnt/beta-catenin pathway, potentially affecting Dapper2 expression.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid can influence Wnt signaling and cellular differentiation, potentially modulating Dapper2 expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin has been shown to modulate the Wnt/beta-catenin pathway, which might influence the expression of Dapper2.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Resveratrol can inhibit Wnt/beta-catenin signaling, potentially impacting Dapper2 expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG, a green tea polyphenol, has been shown to affect the Wnt/beta-catenin pathway, potentially influencing Dapper2 expression.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

As a DNA methyltransferase inhibitor, 5-Azacytidine might modulate the expression of genes, potentially including Dapper2, especially if its expression is epigenetically silenced in certain contexts.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Valproic acid is an HDAC inhibitor that can alter gene expression profiles. It may influence the expression of genes involved in Wnt signaling, including Dapper2.