C4orf14 Activators
The chemical class known as C4orf14 activators encompasses a diverse range of compounds that engage with cellular pathways to enhance the activity of the C4orf14 protein, a component implicated in mitochondrial biogenesis and function. These activators operate through various mechanisms, often through the modulation of signaling pathways and cellular processes that are foundational for mitochondrial health and energy metabolism. By influencing these pathways, these chemicals can augment the activity of proteins associated with mitochondrial dynamics, including C4orf14. For instance, some activators can work by stimulating sirtuins, a family of proteins that play a critical role in the regulation of mitochondrial biogenesis. By activating these sirtuins, the chemicals can initiate a cascade of events leading to enhanced mitochondrial function and, as a consequence, can upregulate the activity of proteins involved in mitochondrial maintenance, including C4orf14.
Moreover, certain activators within this chemical class can function by interacting with peroxisome proliferator-activated receptors (PPARs), which are nuclear receptor proteins that regulate the expression of genes involved in energy metabolism. By activating PPARs, these compounds can enhance fatty acid oxidation and mitochondrial biogenesis, which can have a downstream effect on the C4orf14 protein's activity. Other activators may influence the adenine monophosphate-activated protein kinase (AMPK) pathway, which serves as a cellular energy sensor and regulates metabolic pathways to maintain energy homeostasis. Activation of AMPK can lead to an upsurge in mitochondrial biogenesis and function, which can indirectly increase the activity of C4orf14. Through such diverse mechanisms, these activators ensure the maintenance of a robust and efficient mitochondrial network, thereby supporting the cellular functions in which C4orf14 is involved.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol is known to activate SIRT1, which can enhance mitochondrial biogenesis through the deacetylation of PGC-1α, a key regulator of energy metabolism that could possibly activate C4orf14 in mitochondrial biogenesis. | ||||||
NAD+, Free Acid | 53-84-9 | sc-208084B sc-208084 sc-208084A sc-208084C sc-208084D sc-208084E sc-208084F | 1 g 5 g 10 g 25 g 100 g 1 kg 5 kg | $57.00 $191.00 $302.00 $450.00 $1800.00 $3570.00 $10710.00 | 4 | |
NAD+ is a coenzyme in redox reactions and a substrate for sirtuins and PARPs, which are involved in stress responses and mitochondrial maintenance, which could possibly activate C4orf14. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $31.00 $46.00 $122.00 $204.00 | 5 | |
As a PPAR agonist, bezafibrate can promote fatty acid oxidation and mitochondrial biogenesis, which could possibly activate C4orf14 through increased mitochondrial protein synthesis demand. | ||||||
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Coenzyme Q10 is a component of the electron transport chain and an antioxidant, which may stabilize mitochondrial function and could possibly activate C4orf14 by maintaining optimal mitochondrial health. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
An antioxidant that can also recycle other antioxidants, alpha-lipoic acid can enhance mitochondrial function, which could possibly activate C4orf14 by promoting a healthier mitochondrial environment. | ||||||
Acetyl-L-carnitine chloride | 5080-50-2 | sc-210747 | 1 g | $53.00 | ||
Acetyl-L-carnitine facilitates the transport of fatty acids into mitochondria for β-oxidation and may enhance mitochondrial function and biogenesis, which could possibly activate C4orf14 through increased energy demand and metabolism. | ||||||
Methylene blue | 61-73-4 | sc-215381B sc-215381 sc-215381A | 25 g 100 g 500 g | $43.00 $104.00 $328.00 | 3 | |
Methylene blue can act as an alternative electron carrier in the mitochondrial electron transport chain, possibly supporting C4orf14 by ensuring continued ATP production under conditions where the ETC is compromised. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG from green tea can enhance mitochondrial biogenesis via activation of AMPK pathways, which could lead to an increase in C4orf14 activity as a component of the enhanced mitochondrial machinery. | ||||||
Creatine, anhydrous | 57-00-1 | sc-214774 sc-214774A | 10 mg 50 g | $28.00 $79.00 | 2 | |
Creatine supports mitochondrial function by improving cellular energy storage and ATP availability, which could possibly activate C4orf14 by increasing the overall demand for mitochondrial function and protein synthesis. | ||||||
Pyrroloquinoline quinone | 72909-34-3 | sc-210178 | 1 mg | $243.00 | ||
PQQ can promote mitochondrial biogenesis and protect mitochondria from oxidative stress, which could possibly activate C4orf14 by supporting the generation of new mitochondria where C4orf14 is involved. | ||||||