Date published: 2025-11-27

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Creatine, anhydrous (CAS 57-00-1)

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Alternate Names:
(α-Methylguanido)acetic acid; N-Amidinosarcosine
Application:
Creatine, anhydrous is involved in the rapid production of ATP in skeletal muscle tissue
CAS Number:
57-00-1
Purity:
≥97%
Molecular Weight:
131.13
Molecular Formula:
C4H9N3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Creatine, anhydrous is a form of creatine from which the water molecule has been removed. Creatine plays a role in the production of energy within cells, particularly in muscle tissue. It functions by increasing the formation of adenosine triphosphate (ATP), the primary energy carrier in cells. Creatine acts by donating a phosphate group to adenosine diphosphate (ADP), forming ATP, which can then be used as a source of energy for muscle contractions. Creatine also helps to buffer the buildup of lactic acid in muscles during intense exercise, delaying the onset of muscle fatigue. Creatine may increase the water content within muscle cells, leading to improved muscle hydration and potentially enhancing muscle size and strength. Its mechanism of action involves increasing the availability of ATP and promoting muscle energy metabolism, ultimately supporting physical performance during high-intensity, short-duration activities.


Creatine, anhydrous (CAS 57-00-1) References

  1. Creatine and creatinine metabolism.  |  Wyss, M. and Kaddurah-Daouk, R. 2000. Physiol Rev. 80: 1107-213. PMID: 10893433
  2. [Creatine: the nutritional supplement for exercise - current concepts].  |  Mendes, RR. and Tirapegui, J. 2002. Arch Latinoam Nutr. 52: 117-27. PMID: 12184144
  3. Effect of creatine and weight training on muscle creatine and performance in vegetarians.  |  Burke, DG., et al. 2003. Med Sci Sports Exerc. 35: 1946-55. PMID: 14600563
  4. Creatine: endogenous metabolite, dietary, and therapeutic supplement.  |  Brosnan, JT. and Brosnan, ME. 2007. Annu Rev Nutr. 27: 241-61. PMID: 17430086
  5. Creatine in mouse models of neurodegeneration and aging.  |  Klopstock, T., et al. 2011. Amino Acids. 40: 1297-303. PMID: 21390530
  6. Studies on the safety of creatine supplementation.  |  Kim, HJ., et al. 2011. Amino Acids. 40: 1409-18. PMID: 21399917
  7. Creatine as a therapeutic strategy for myopathies.  |  Tarnopolsky, MA. 2011. Amino Acids. 40: 1397-407. PMID: 21399918
  8. The creatine kinase system and pleiotropic effects of creatine.  |  Wallimann, T., et al. 2011. Amino Acids. 40: 1271-96. PMID: 21448658
  9. Creatine Supplementation and Lower Limb Strength Performance: A Systematic Review and Meta-Analyses.  |  Lanhers, C., et al. 2015. Sports Med. 45: 1285-1294. PMID: 25946994
  10. Creatine Supplementation and Upper Limb Strength Performance: A Systematic Review and Meta-Analysis.  |  Lanhers, C., et al. 2017. Sports Med. 47: 163-173. PMID: 27328852
  11. Diagnostic and Pharmacological Potency of Creatine in Post-Viral Fatigue Syndrome.  |  Ostojic, SM. 2021. Nutrients. 13: PMID: 33557013
  12. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show?  |  Antonio, J., et al. 2021. J Int Soc Sports Nutr. 18: 13. PMID: 33557850
  13. Anti-Inflammatory and Anti-Catabolic Effects of Creatine Supplementation: A Brief Review.  |  Cordingley, DM., et al. 2022. Nutrients. 14: PMID: 35276903
  14. Creatine and its application as an ergogenic aid.  |  Greenhaff, PL. 1995. Int J Sport Nutr. 5 Suppl: S100-10. PMID: 7550252

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Creatine, anhydrous, 10 mg

sc-214774
10 mg
$27.00

Creatine, anhydrous, 50 g

sc-214774A
50 g
$77.00