Date published: 2026-4-24

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ARL5A Activators

ARL5A, also known as ADP-ribosylation factor-like 5A, is a member of the ARF-like protein (ARL) family, which is part of the larger Ras superfamily of GTPases. These proteins play crucial roles in a variety of cellular processes such as intracellular trafficking, cell growth, and signal transduction. ARL5A, specifically, has been found to localize to the mitochondria and Golgi apparatus in cells, suggesting its involvement in the regulation of these organelles' functions. While the exact functions of ARL5A remain to be fully elucidated, it's likely that ARL5A plays a significant role in maintaining cellular homeostasis.

Given the central role of GTPases in cellular signaling and regulation, numerous chemical compounds could induce the expression of ARL5A.

Hormones such as estradiol, testosterone, and progesterone, which are known to modulate gene expression related to cell growth and development, might influence ARL5A expression. For instance, these hormones could stimulate ARL5A expression as part of the intracellular response to hormone signals. Similarly, compounds like retinoic acid and vitamin D, which regulate gene expression related to cellular differentiation and immune function, could also upregulate ARL5A. Moreover, substances like cyclic AMP (cAMP) and dexamethasone, which have broad effects on cellular metabolism and stress responses respectively, might also stimulate the expression of ARL5A.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic Acid may upregulate ARL5B expression due to its role in the control of gene expression related to cellular differentiation and development. As a potent regulator of cell growth and differentiation, retinoic acid could induce ARL5B expression as part of the cellular adaptation to differentiation cues.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone might stimulate ARL5B expression through its broad effects on gene expression related to cellular stress responses and inflammation. As a potent anti-inflammatory agent, dexamethasone could induce ARL5B expression as part of the cellular response to stress or inflammation.

β-Estradiol

50-28-2sc-204431
sc-204431A
500 mg
5 g
$63.00
$182.00
8
(1)

β-Estradiol could induce ARL5B expression due to its role in the regulation of numerous genes related to cell growth and development. As a key hormone in the regulation of female reproductive functions, estradiol may stimulate ARL5B expression as part of the intracellular response to hormone signals.

Progesterone

57-83-0sc-296138A
sc-296138
sc-296138B
1 g
5 g
50 g
$20.00
$52.00
$298.00
3
(1)

Progesterone might increase ARL5B expression as part of its role in the regulation of gene expression during the cell cycle. Given its role in preparing the body for pregnancy, progesterone could stimulate ARL5B expression as part of the cellular adaptations that occur during the menstrual cycle.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$71.00
$163.00
$296.00
2
(1)

Vitamin D (Cholecalciferol) could upregulate ARL5B expression due to its role in the regulation of gene expression related to cellular differentiation and immune function. As Vitamin D is essential for bone health and immune function, it could stimulate ARL5B expression as part of the cellular response to vitamin D intake.

Adenosine 3′,5′-cyclic monophosphate

60-92-4sc-217584
sc-217584A
sc-217584B
sc-217584C
sc-217584D
sc-217584E
100 mg
250 mg
5 g
10 g
25 g
50 g
$116.00
$179.00
$265.00
$369.00
$629.00
$1150.00
(1)

cAMP (Adenosine 3',5'-cyclic monophosphate) might stimulate the expression of ARL5B as it serves as a second messenger in numerous signaling pathways, potentially requiring increased GTPase activity. Given its role in the regulation of glycogen and lipid metabolism, cAMP could induce ARL5B expression as part of the cellular response to metabolic signals.