ARL5A Antibody (G-9): sc-514680
- ARL5A Antibody (G-9) is a mouse monoclonal IgG1 κ ARL5A antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 92-179 mapping at the C-terminus of ARL5A of human origin
- ARL5A Antibody (G-9) is recommended for detection of ARL5A of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ARL5A Antibody (G-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARL5A Antibody (G-9) for WB applications. These reagents are now offered in bundles with ARL5A Antibody (G-9) (see ordering information below).
ARL5A Antibody (G-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARL5A of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARL5A monoclonal antibody (G-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARL5A, also known as ADP-ribosylation factor-like protein 5, consists of 179 amino acids and is a member of the highly conserved ADP-ribosylation factor family, which plays a crucial role in eukaryotic vesicular trafficking pathways. While many ARF family members enhance the activity of ADP-ribosyltransferases, ARL5A is unique in lacking this enhancing activity. Nuclear localization of ARL5A is significant, as ARL5A has been shown to interact with heterochromatin protein 1 alpha (HP1α), suggesting a potential role in nuclear dynamics and embryonic development signaling pathways. ARL5A participation in these processes underscores ARL5A′s importance in cellular function and development, making anti-ARL5A antibody (G-9) a valuable tool for researchers studying these critical biological mechanisms.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ARL5A Antibody (G-9) References:
- A developmentally regulated ARF-like 5 protein (ARL5), localized to nuclei and nucleoli, interacts with heterochromatin protein 1. | Lin, CY., et al. 2002. J Cell Sci. 115: 4433-45. PMID: 12414990
- Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication. | Pasqualato, S., et al. 2002. EMBO Rep. 3: 1035-41. PMID: 12429613
- Identification and characterization of nine novel human small GTPases showing variable expressions in liver cancer tissues. | He, H., et al. 2002. Gene Expr. 10: 231-42. PMID: 12450215
- RASL11A, member of a novel small monomeric GTPase gene family, is down-regulated in prostate tumors. | Louro, R., et al. 2004. Biochem Biophys Res Commun. 316: 618-27. PMID: 15033445
- Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation. | Okai, T., et al. 2004. J Cell Sci. 117: 4705-15. PMID: 15331635
- 2.0 A crystal structure of human ARL5-GDP3'P, a novel member of the small GTP-binding proteins. | Wang, ZX., et al. 2005. Biochem Biophys Res Commun. 332: 640-5. PMID: 15896705
- Arf family GTPases: roles in membrane traffic and microtubule dynamics. | Kahn, RA., et al. 2005. Biochem Soc Trans. 33: 1269-72. PMID: 16246095
- Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins. | Kahn, RA., et al. 2006. J Cell Biol. 172: 645-50. PMID: 16505163
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARL5A Antibody (G-9) | sc-514680 | 200 µg/ml | $316.00 | |||
ARL5A Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-531191 | 200 µg Ab; 10 µg BP | $354.00 | |||
ARL5A Antibody (G-9): m-IgGκ BP-HRP Bundle | sc-524811 | 200 µg Ab, 40 µg BP | $354.00 | |||
ARL5A Antibody (G-9) AC | sc-514680 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ARL5A Antibody (G-9) HRP | sc-514680 HRP | 200 µg/ml | $316.00 | |||
ARL5A Antibody (G-9) FITC | sc-514680 FITC | 200 µg/ml | $330.00 | |||
ARL5A Antibody (G-9) PE | sc-514680 PE | 200 µg/ml | $343.00 | |||
ARL5A Antibody (G-9) Alexa Fluor® 488 | sc-514680 AF488 | 200 µg/ml | $357.00 | |||
ARL5A Antibody (G-9) Alexa Fluor® 546 | sc-514680 AF546 | 200 µg/ml | $357.00 | |||
ARL5A Antibody (G-9) Alexa Fluor® 594 | sc-514680 AF594 | 200 µg/ml | $357.00 | |||
ARL5A Antibody (G-9) Alexa Fluor® 647 | sc-514680 AF647 | 200 µg/ml | $357.00 | |||
ARL5A Antibody (G-9) Alexa Fluor® 680 | sc-514680 AF680 | 200 µg/ml | $357.00 | |||
ARL5A Antibody (G-9) Alexa Fluor® 790 | sc-514680 AF790 | 200 µg/ml | $357.00 |