Date published: 2026-7-10

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synuclein Antibodies

Santa Cruz Biotechnology delivers a wide array of synuclein monoclonal antibodies for various research applications. synuclein Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Synucleins are a family of proteins, including alpha-synuclein, beta-synuclein, and gamma-synuclein, which influence synaptic function and neurotransmitter release. Alpha-synuclein is notably associated with neurodegenerative diseases such as Parkinson's disease, making it a key target for research aimed at understanding these conditions. The study of synuclein proteins reveals important insights into neuronal health and disease mechanisms. Researchers worldwide utilize synuclein monoclonal antibodies to explore protein expression patterns and cellular localization. Advanced detection methods, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC) conjugates, enable precise visualization of synuclein proteins. Understanding synuclein behavior and interactions continues to drive neuroscience research forward. Santa Cruz Biotechnology monoclonal antibodies support researchers in their mission to unlock the mysteries of neurodegenerative diseases and advance scientific knowledge.

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synuclein Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

alpha Synuclein Antibody (211)

sc-12767mouse IgG1 κ121-125 (h)WB, IP, IF, IHC(P)h
220
(29)

alpha Synuclein Antibody (2B2D1)

sc-53955mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
8
(9)

alpha Synuclein Antibody (3H2897)

sc-69977mouse IgG1FL (h)WB, IP, IF, IHC(P)m, r, h
39
(10)

alpha Synuclein Antibody (LB 509)

sc-58480mouse IgG1 κ(h)WB, IP, IF, IHC(P)h
30
(5)

alpha Synuclein Antibody (Syn 204)

sc-32280mouse IgG2a κ(h)WB, IP, IF, IHC(P)h
9
(8)

alpha Synuclein Antibody (3G282)

sc-69978mouse IgG1 κ(h)WB, IP, IF, IHC(P)h

new

(1)

alpha Synuclein Antibody (D-10)

sc-515879mouse IgG2a κ112-140 (h)WB, IP, IF, ELISAm, r, h
4
(1)

alpha/beta Synuclein Antibody (Syn 202)

sc-32281mouse IgG2a κ(h)WB, IP, IF, IHC(P)m, r, h
3
(3)

beta Synuclein Antibody (8)

sc-136452mouse IgG1 κ107-118 (r)WB, IPm, r, h
6
(1)

gamma Synuclein/SNCG Antibody (1H10D2)

sc-65979mouse IgG1 κ(h)WB, IP, IF, IHC(P)m, r, h
9
(4)

gamma Synuclein/SNCG Antibody (8H11)

sc-135575mouse IgG2a κ21-127 (h)WB, IP, ELISAh

new

(2)

nitrated alpha Synuclein Antibody (Syn514)

sc-32279mouse IgG1 κoxidized α-synuclein (h)WB, IP, IFm, r, h
5
(1)

nitrated alpha Synuclein Antibody (4H316)

sc-71703mouse IgG1 κ(h)WB, IP, IFm, r, h

new

(1)

nitrated alpha/beta Synuclein Antibody (4H317)

sc-71702mouse IgG1 κ(h)WB, IP, IF, IHC(P)h

new

(1)

nitrated alpha/beta Synuclein Antibody (Syn12)

sc-32278mouse IgG1 κ(h)WB, IP, IF, IHC(P)h

new

(1)

synuclein siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

alpha Synuclein siRNA (h)

sc-29619hGene SilencingN/A
11
(0)

alpha Synuclein shRNA Plasmid (h)

sc-29619-SHhGene SilencingPuromycin
11
(0)

alpha Synuclein shRNA (h) Lentiviral Particles

sc-29619-VhGene SilencingPuromycin
11
(0)

alpha Synuclein siRNA (m)

sc-42286mGene SilencingN/A0
(0)

alpha Synuclein shRNA Plasmid (m)

sc-42286-SHmGene SilencingPuromycin0
(0)

alpha Synuclein shRNA (m) Lentiviral Particles

sc-42286-VmGene SilencingPuromycin0
(0)

alpha/beta Synuclein siRNA (h)

sc-43589hGene SilencingN/A0
(0)

alpha/beta Synuclein shRNA Plasmid (h)

sc-43589-SHhGene SilencingPuromycin0
(0)

alpha/beta Synuclein shRNA (h) Lentiviral Particles

sc-43589-VhGene SilencingPuromycin0
(0)

beta Synuclein siRNA (h)

sc-36594hGene SilencingN/A
4
(0)

beta Synuclein shRNA Plasmid (h)

sc-36594-SHhGene SilencingPuromycin
4
(0)

beta Synuclein shRNA (h) Lentiviral Particles

sc-36594-VhGene SilencingPuromycin
4
(0)

beta Synuclein siRNA (m)

sc-36595mGene SilencingN/A0
(0)

beta Synuclein shRNA Plasmid (m)

sc-36595-SHmGene SilencingPuromycin0
(0)

beta Synuclein shRNA (m) Lentiviral Particles

sc-36595-VmGene SilencingPuromycin0
(0)

gamma Synuclein/SNCG siRNA (h)

sc-42289hGene SilencingN/A0
(0)

gamma Synuclein/SNCG shRNA Plasmid (h)

sc-42289-SHhGene SilencingPuromycin0
(0)

gamma Synuclein/SNCG shRNA (h) Lentiviral Particles

sc-42289-VhGene SilencingPuromycin0
(0)

gamma Synuclein/SNCG siRNA (m)

sc-42290mGene SilencingN/A
1
(0)

gamma Synuclein/SNCG shRNA Plasmid (m)

sc-42290-SHmGene SilencingPuromycin
1
(0)

gamma Synuclein/SNCG shRNA (m) Lentiviral Particles

sc-42290-VmGene SilencingPuromycin
1
(0)

synuclein Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

alpha Synuclein (h): 293T Lysate

sc-111729h0
(0)

synuclein CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

alpha Synuclein CRISPR/Cas9 KO Plasmid (h)

sc-417273Gene Knockouth0
(0)

alpha Synuclein HDR Plasmid (h)

sc-417273-HDRHomology Directed Repairh0
(0)

beta Synuclein CRISPR/Cas9 KO Plasmid (h)

sc-400894Gene Knockouth0
(0)

beta Synuclein HDR Plasmid (h)

sc-400894-HDRHomology Directed Repairh0
(0)

gamma Synuclein/SNCG CRISPR/Cas9 KO Plasmid (h)

sc-401050Gene Knockouth0
(0)

synuclein CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

alpha Synuclein Double Nickase Plasmid (h)

sc-417273-NICGene Knockouth0
(0)

alpha Synuclein Double Nickase Plasmid (h2)

sc-417273-NIC-2Gene Knockouth0
(0)

alpha Synuclein Double Nickase Plasmid (m)

sc-423051-NICGene Knockoutm0
(0)

beta Synuclein Double Nickase Plasmid (h)

sc-400894-NICGene Knockouth0
(0)

beta Synuclein Double Nickase Plasmid (h2)

sc-400894-NIC-2Gene Knockouth0
(0)

beta Synuclein Double Nickase Plasmid (m)

sc-430508-NICGene Knockoutm0
(0)

beta Synuclein Double Nickase Plasmid (m2)

sc-430508-NIC-2Gene Knockoutm0
(0)

synuclein CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

alpha Synuclein CRISPR Activation Plasmid (h)

sc-417273-ACTGene Activationh0
(0)

alpha Synuclein CRISPR Activation Plasmid (h2)

sc-417273-ACT-2Gene Activationh0
(0)

alpha Synuclein Lentiviral Activation Particles (h)

sc-417273-LACGene Activationh0
(0)

alpha Synuclein CRISPR Activation Plasmid (m)

sc-423051-ACTGene Activationm0
(0)

beta Synuclein CRISPR Activation Plasmid (h)

sc-400894-ACTGene Activationh0
(0)

beta Synuclein CRISPR Activation Plasmid (h2)

sc-400894-ACT-2Gene Activationh0
(0)

gamma Synuclein/SNCG CRISPR Activation Plasmid (h)

sc-401050-ACTGene Activationh0
(0)